Propose a reaction scheme for the synthesis of the following ethers through the Williamson synthesis. Use an alkyl bromide or alkyl chloride in your reactions. 1. methyl propyl ether 2. methoxycyclohexane
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- how how you would use the Williamson ether synthesis to prepare the following ethers.You may use any alcohols or phenols as your organic starting materials. 1-methoxy-4-nitrobenzeneShow how you might use the Williamson ether synthesis to prepare each ether. (a) (b)Give one example of Williamson ether synthesis. Show the reactants materials and the product. Draw the reaction mechanism?
- What reagents/conditions would this ether synthesis require?Show how you would use the Williamson ether synthesis to prepare the following ethers.You may use any alcohols or phenols as your organic starting materials. ) isopropyl methyl etherShow how you would use the Williamson ether synthesis to prepare the following ethers.You may use any alcohols or phenols as your organic starting materials.(a) cyclohexyl propyl ether
- Besides the tert-butyldimethylsilyl ethers, there are many other widely used alcohol protecting groups. For example, an alcohol such as cyclohexanol can be converted to a methoxy methyl ether (a MOM protecting group) by treatment with base and chloromethyl methyl ether, ClCH2OCH3. The protecting group can be removed by treatment with aqueous acid.a. Write a stepwise mechanism for the formation of a MOM ether from cyclohexanol.b. What functional group comprises a MOM ether?c. Besides cyclohexanol, what other products are formed by aqueous hydrolysis of the MOM ether? Draw a stepwise mechanism that accounts for formation of each product.Show how the following ethers might be synthesized using (1) alkoxymercuration–demercuration and (2) the Williamson synthesis. (When one of these methods cannot beused for the given ether, point out why it will not work.)(a) 2-methoxybutane (b) ethyl cyclohexyl etherI cyclohexanone II cyclohexanol III methylcyclohexanol. (b) Arrange the above compounds in the order of increasing boiling point. Explain. thank you for helping me.
- II. Alcohols in Synthesis B.) How are alcohols used to make ethers in the Williamson ether synthesis? How do you design the synthesis of ethers using both acidic and basic Williamson ether synthesis strategies?Draw the structure of the two ketones which may be used to make the tertiary alcohol shown below by reaction with a Grignard reagent.Starting from cyclohexanol, show how to prepare: Show all reagents and molecules synthesized along the way after each step. You do not have to use curved arrows.