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- Explain about the BLAST (Basic Local Alignment Search Tool) ?What are the limitations of BLAST (Basic Local Alignment Search Tool)?Q. What is the best analysis for estimation of family sequence conservation of domains? Enlist any two tools through which we can perform this task? (Subject Bioinformatics).
- Provide five advantages of Next Generation Sequencing? and explain each of these advantages.Explain the two-dimensional gel electrophoresis (2DGE) ?Is there any difference between the alignments, alignment scores, identity percentages, positives and gaps? If so, what is your explanation for the differences?
- How to isolate cpDNA for whole chloroplast DNA sequencing (MiSeq system)? Any universal primer or cpDNA extraction kit support for this?In this qPCR plot, which sample had theleast abundant starting amount of DNA?Discuss the importance of linkage disequilibrium (LD) toassociation mapping of QTLs in humans.
- Hi, I would like to know which program is used for the graphical presentation of the results of a meta-analysis of genome-wide linkage scans?If it is not possible to have three bands for one STR region when looking at the DNA from one individual, then how many different STR regions were sampled in the gel electrophoresis simulation to end up with three bands on the gel? Note: there are several correct answers.Explain why DNA fragments migrate in a gel electrophoresis. Which fragments migrate farthest: large or small?