Sample 07 is from the half-brother of Missing Fisherman #2. They share a father but have different mothers. If samples 01 or 02 are from Fisherman #2, how many STR variations would you expect the half brothers to share? a. Do any of the variations at 16 STR loci suggest that sample 07 and Samples 01 or 02 have the same father? b. Do any of the variations at 16 STR loci suggest that sample 07 and Samples 01 or 02 have the a different father?

Case Studies In Health Information Management
3rd Edition
ISBN:9781337676908
Author:SCHNERING
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Chapter6: Leadership
Section: Chapter Questions
Problem 6.18.4C
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Sample 07 is from the half-brother of Missing Fisherman #2. They share a father but have different mothers. If samples 01 or 02 are from Fisherman #2, how many STR variations would you expect the half brothers to share?

a. Do any of the variations at 16 STR loci suggest that sample 07 and Samples 01 or 02 have the same father?

b. Do any of the variations at 16 STR loci suggest that sample 07 and Samples 01 or 02 have the a different father?

Handout 2-4: Forensic DNA Analysis for Shark Scenario
Summary of STR Results.
Sample
04
(Reference)
15
7,9.3
30, 31
17, 19
{8, 17}
12, 13
13
9, 11
8,9
11, 12
8, 12
X, Y
X
VWA
15, *
16
D8S1179
15
13, 15
TPOX
{8,9}
8,11
FGA
24, 25
24, 25
20, 24
*peak(s) present below reporting threshold; locus not used for comparison
{}= peak imbalance present
INC = locus inconclusive; not used in comparison
NR = no results
¹Sample 07 represents the fisherman's half-brother; he shares the same father but has a different mother.
Locus
D3S1358
TH01
D21S11
D18S51
Penta E
D5S818
D13S317
D7S820
D16S539
CSF1PO
Penta D
Amelogenin
01
(Tissue)
14, 16
6, 9.3
29, 30
12, 16
INC
8, 10
11, 12
10, 11
INC
7,12
INC
02
(Bone)
14, 16
6,9.3
29, 30
12, 16
8,9
8, 10
11, 12
10, 11
10, 12
7,12
2.2,9
X, Y
15, 19
15
8,9
Sample Codes:
01 = Tissue remains found in shark
02= Bone remains found in shark
03 = Tissue remains found in shark
03
(Tissue)
NR
05
(Reference)
16
7,9.3
30, 31.2
12, 13
5, 13
11, 12
12, 13
9, 12
8, 11
9, 11
8, 14
X, Y
14, 16
14, 15
8,11
22, 25
06
(Reference)
16
7,9.3
29, 30
12, 16
9, 11
10, 11
11
9, 10
11, 12
7,11
5,9
X
16, 19
14, 15
8,9
22, 24
07
(Reference)¹
15, 17
6
29, 32.2
16, 18
13, 15
13
11, 12
10, 12
10, 11
11, 12
9, 11
X, Y
14, 16
12
8
21, 25
04 Daughter of missing fisherman #1
05 = Son of missing fisherman #1
06 = Mother of missing fisherman #2
07 = Half-brother of missing fisherman #2
Transcribed Image Text:Handout 2-4: Forensic DNA Analysis for Shark Scenario Summary of STR Results. Sample 04 (Reference) 15 7,9.3 30, 31 17, 19 {8, 17} 12, 13 13 9, 11 8,9 11, 12 8, 12 X, Y X VWA 15, * 16 D8S1179 15 13, 15 TPOX {8,9} 8,11 FGA 24, 25 24, 25 20, 24 *peak(s) present below reporting threshold; locus not used for comparison {}= peak imbalance present INC = locus inconclusive; not used in comparison NR = no results ¹Sample 07 represents the fisherman's half-brother; he shares the same father but has a different mother. Locus D3S1358 TH01 D21S11 D18S51 Penta E D5S818 D13S317 D7S820 D16S539 CSF1PO Penta D Amelogenin 01 (Tissue) 14, 16 6, 9.3 29, 30 12, 16 INC 8, 10 11, 12 10, 11 INC 7,12 INC 02 (Bone) 14, 16 6,9.3 29, 30 12, 16 8,9 8, 10 11, 12 10, 11 10, 12 7,12 2.2,9 X, Y 15, 19 15 8,9 Sample Codes: 01 = Tissue remains found in shark 02= Bone remains found in shark 03 = Tissue remains found in shark 03 (Tissue) NR 05 (Reference) 16 7,9.3 30, 31.2 12, 13 5, 13 11, 12 12, 13 9, 12 8, 11 9, 11 8, 14 X, Y 14, 16 14, 15 8,11 22, 25 06 (Reference) 16 7,9.3 29, 30 12, 16 9, 11 10, 11 11 9, 10 11, 12 7,11 5,9 X 16, 19 14, 15 8,9 22, 24 07 (Reference)¹ 15, 17 6 29, 32.2 16, 18 13, 15 13 11, 12 10, 12 10, 11 11, 12 9, 11 X, Y 14, 16 12 8 21, 25 04 Daughter of missing fisherman #1 05 = Son of missing fisherman #1 06 = Mother of missing fisherman #2 07 = Half-brother of missing fisherman #2
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