sarcolemma Ex 201 ion channel Nas myosin cross bridge Nat acetylcholine axon axon sarcolemma ion channel DOPOCE Na+ Net sarcoplasmic reticulum axon sarcolemma ion channel PEX troponin/ tropomyosin axon sarcolemma ion channel Na+ myofibril action potential action potential Nas Na+ axon axon sarcolemma ion channel sarcolemma ion channel Nat Pack
Order the steps of the neuromuscular junction transmission using the following images. Then, usethe to describe what is happening in the step.
Neuromuscular Junction Transmission - Contraction
1. Action potential travels from motor neuron cell body along the myelinated axon to neuromuscular junction.
2. Acetylcholine (ACh) is released from axon (neuron), crosses synapse (space between axon and sarcolemma).
ACh binds to ACh receptors (channel) in sarcolemma.
3.ACh channels open. Ions (like sodium, Na+) flow into sarcolemma.
Action potential spreads in sarcolemma and into transverse tubules.
4. Action potential causes the release of calcium (Ca2+) from sarcoplasmic reticulum into sarcoplasm
5.Ca2+ goes to the troponin, which moves the tropomyosin away from actin
6. Myosin head breaks down ATP, causing the sliding filament mechanism to shorten sarcomere
Muscle contracts
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