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- A mutation that eliminated the wild type function of PRE would be most consistent with... Select one or more: a. successful infection of an E. coli with a lamB mutation. b. loss of lysogeny c. loss of switch from prophage to lytic cycle d. ?virwhich of the following is true regarding UP elements? A. Occur between -40 and -60 of an E. coli promoter B. Occur in weak promoters C. Interact with the sigma factor of the RNA polymerase D. None of the above"CRISPR-Cas9 was discovered as bacterial defense mechanism that targets and destroys foreign plasmids and viruses. Cas9 cleaves the target, and exonuclease degradation occurs." The 1st statement is True and the 2nd statement is False. The 1st statement is False and the 2nd statement is True. Both Staments are True. Both statements are False.