Show complete solutions and round off your answers up to 4 decimal places. A prospective study on the relationship between aspirin use and heart attacks by the Physicians' Health Study Research Group at Harvard Medical School is presented below. The Physicians' Health Study was a 5-year randomized study of whether regular aspirin intake reduces risk of myocardial infarction or heart attack. Every other day, physicians participating in the study took either one aspirin tablet or a placebo. The study was blind those in the study did not know whether they were taking aspirin or a placebo. Of the 11,034 physicians taking a placebo, 189 suffered heart attacks over the course of the study, whereas of the 11,037 taking aspirin, 104 had heart attacks. Can we say that the intake of aspirin appears to diminish the risk of myocardial infarction? Myocardial Infarction No Group Total Yes Placebo 189 Aspirin 104 Total 293 10845 11034 10933 11037 21778 22071 Let patients taking placebo be the first group and those taking aspirin in the second group. Calculate the following and make an interpretation: 1. risk difference 2. relative risk 3. odds ratio
Show complete solutions and round off your answers up to 4 decimal places. A prospective study on the relationship between aspirin use and heart attacks by the Physicians' Health Study Research Group at Harvard Medical School is presented below. The Physicians' Health Study was a 5-year randomized study of whether regular aspirin intake reduces risk of myocardial infarction or heart attack. Every other day, physicians participating in the study took either one aspirin tablet or a placebo. The study was blind those in the study did not know whether they were taking aspirin or a placebo. Of the 11,034 physicians taking a placebo, 189 suffered heart attacks over the course of the study, whereas of the 11,037 taking aspirin, 104 had heart attacks. Can we say that the intake of aspirin appears to diminish the risk of myocardial infarction? Myocardial Infarction No Group Total Yes Placebo 189 Aspirin 104 Total 293 10845 11034 10933 11037 21778 22071 Let patients taking placebo be the first group and those taking aspirin in the second group. Calculate the following and make an interpretation: 1. risk difference 2. relative risk 3. odds ratio
Chapter22: Pharmacology
Section: Chapter Questions
Problem H1CRE
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Transcribed Image Text:Show complete solutions and round off your answers up to 4 decimal places.
A prospective study on the relationship between aspirin use and heart attacks by the
Physicians' Health Study Research Group at Harvard Medical School is presented below.
The Physicians' Health Study was a 5-year randomized study of whether regular aspirin
intake reduces risk of myocardial infarction or heart attack. Every other day, physicians
participating in the study took either one aspirin tablet or a placebo. The study was blind
those in the study did not know whether they were taking aspirin or a placebo.
Of the 11,034 physicians taking a placebo, 189 suffered heart attacks over the course of
the study, whereas of the 11,037 taking aspirin, 104 had heart attacks. Can we say that the
intake of aspirin appears to diminish the risk of myocardial infarction?
Myocardial Infarction
No
Group
Total
Yes
Placebo 189
Aspirin 104
Total 293
10845
11034
10933
11037
21778
22071
Let patients taking placebo be the first group and those taking aspirin in the second
group. Calculate the following and make an interpretation:
1. risk difference
2. relative risk
3. odds ratio
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