Structure of lactam.. 1) Why this lactam would be evolutionarily selected against? a. Amino acids with rings are selected against. b. The lactam would cause cleavage of the peptide. c. There are not enough codons to encode an additional amino acid. d. The bulkiness of the side chain.

Essentials of Pharmacology for Health Professions
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ISBN:9781305441620
Author:WOODROW
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Chapter5: Abbreviations And Systems Of Measurement
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Structure of lactam..

1) Why this lactam would be evolutionarily selected against?

a. Amino acids with rings are selected against.

b. The lactam would cause cleavage of the peptide.

c. There are not enough codons to encode an additional amino acid.

d. The bulkiness of the side chain.

 

2) Lysine is similar to ornithine. Why does lysine not form a lactam?

a. Infrequency of lysine occurring in proteins.

b. Size of the ring formed.

c. Charge on the primary amine.

d. Formation of salt bridges with anionic amino acids..

H3C.
`NH
IZ
Transcribed Image Text:H3C. `NH IZ
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