The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COO™ COO™ H₂N-CH H₂N-CH CH H CH N bbbb 6.0 CH H N COOH H₂N-CH CH₂ H -N CH lonizable -COOH group 1.8 COO -HisH+ -His CH -NH COO™ H₂N-CH 9.2 CH, H H N -NH₂ CH A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?
The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COO™ COO™ H₂N-CH H₂N-CH CH H CH N bbbb 6.0 CH H N COOH H₂N-CH CH₂ H -N CH lonizable -COOH group 1.8 COO -HisH+ -His CH -NH COO™ H₂N-CH 9.2 CH, H H N -NH₂ CH A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?
General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter20: Proteins
Section: Chapter Questions
Problem 20.48EP: Most amino acids have isoelectric points between 5.0 and 6.0, but the isoelectric point of lysine is...
Related questions
Question
![The amino acid histidine has ionizable groups with pKą values of 1.8, 6.0, and 9.2, as shown.
H₂N-CH
T
COOH
pH
CH₂ H
lonizable -COOH
group
=
CH
COO-
H₂N-CH
1.8
pk₁
CH2
-COO-
H
-N
CH
-HisH+
COO-
+
H₂N-CH
6.0
pk₂
CH2
-His
CH
-NH
COO-
H₂N-CH
9.2
pk3
CH2
-N
-NH₂
A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is
the pH of the resulting solution?
CH](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fdc07c092-5f49-4d93-b501-b08294061775%2F27c6cd75-dbd0-4258-be86-93dd74448de1%2Fckzgv5n_processed.png&w=3840&q=75)
Transcribed Image Text:The amino acid histidine has ionizable groups with pKą values of 1.8, 6.0, and 9.2, as shown.
H₂N-CH
T
COOH
pH
CH₂ H
lonizable -COOH
group
=
CH
COO-
H₂N-CH
1.8
pk₁
CH2
-COO-
H
-N
CH
-HisH+
COO-
+
H₂N-CH
6.0
pk₂
CH2
-His
CH
-NH
COO-
H₂N-CH
9.2
pk3
CH2
-N
-NH₂
A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is
the pH of the resulting solution?
CH
Expert Solution
![](/static/compass_v2/shared-icons/check-mark.png)
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 4 steps with 35 images
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
![General, Organic, and Biological Chemistry](https://www.bartleby.com/isbn_cover_images/9781285853918/9781285853918_smallCoverImage.gif)
General, Organic, and Biological Chemistry
Chemistry
ISBN:
9781285853918
Author:
H. Stephen Stoker
Publisher:
Cengage Learning
![Organic And Biological Chemistry](https://www.bartleby.com/isbn_cover_images/9781305081079/9781305081079_smallCoverImage.gif)
Organic And Biological Chemistry
Chemistry
ISBN:
9781305081079
Author:
STOKER, H. Stephen (howard Stephen)
Publisher:
Cengage Learning,
![Introduction to General, Organic and Biochemistry](https://www.bartleby.com/isbn_cover_images/9781285869759/9781285869759_smallCoverImage.gif)
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:
9781285869759
Author:
Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:
Cengage Learning
![General, Organic, and Biological Chemistry](https://www.bartleby.com/isbn_cover_images/9781285853918/9781285853918_smallCoverImage.gif)
General, Organic, and Biological Chemistry
Chemistry
ISBN:
9781285853918
Author:
H. Stephen Stoker
Publisher:
Cengage Learning
![Organic And Biological Chemistry](https://www.bartleby.com/isbn_cover_images/9781305081079/9781305081079_smallCoverImage.gif)
Organic And Biological Chemistry
Chemistry
ISBN:
9781305081079
Author:
STOKER, H. Stephen (howard Stephen)
Publisher:
Cengage Learning,
![Introduction to General, Organic and Biochemistry](https://www.bartleby.com/isbn_cover_images/9781285869759/9781285869759_smallCoverImage.gif)
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:
9781285869759
Author:
Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:
Cengage Learning
![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9781305080485/9781305080485_smallCoverImage.gif)
![Chemistry: Principles and Reactions](https://www.bartleby.com/isbn_cover_images/9781305079373/9781305079373_smallCoverImage.gif)
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning