The failure of chromosome 21 to segregate during egg or sperm development produces a gamete with 24 chromosomes. This mutated gamete, when fused with a normal gamete, results in a fetus with an extra copy of chromosome 21. Which type of mutation during cell division is responsible for the occurrence of this disorder? deletion

The failure of chromosome 21 to segregate during egg or sperm development produces a gamete with 24 chromosomes. This mutated gamete, when fused with a normal gamete, results in a fetus with an extra copy of chromosome 21. Which type of mutation during cell division is responsible for the occurrence of this disorder? deletion

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter11: Meiosis: The Cellular Basis Of Sexual Reproduction

Section: Chapter Questions

Problem 1TYK: The chromosome constitution number of this individual is 2=6. This drawing represents: a. mitotic...

See similar textbooks

Similar questions

A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13. In discussing this discovery with a friend who is not a cytogeneticist, explain how you would describe this location, defining each term in the chromosome address 21q13.
People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes. However, in a few cases of Down syndrome, 46 chromosomes are present. This total includes two normal-looking chromosomes 21, one normal chromosome 14, and a longer-than-normal chromosome 14. Interpret this observation. How can these individuals have 46 chromosomes?
The chromosome constitution number of this individual is 2=6. This drawing represents: a. mitotic metaphase. b. meiotic metaphase I. c. meiotic metaphase II. d. a gamete. e. sixnonhomologous chromosomes.
Obvious differences in the position of chromosome copies are clear during metaphase of mitosis and meiosis. How would you describe these changes?
___________ chromosome aneuploidy is usually welltolerated because only one X chromosomeremains active and because the Y chromosomehas few genes
A male Drosophila from a wild-type stock is discovered to haveonly seven chromosomes, whereas normally 2n = 8. Closeexamination reveals that one member of chromosome IV (thesmallest chromosome) is attached to (translocated to) the distalend of chromosome II and is missing its centromere, thusaccounting for the reduction in chromosome number. (a) Diagram all members of chromosomes II and IV duringsynapsis in meiosis I.
Humans have 46 chromosomes in each somatic cell.a. How many chromosomes does a child receive fromits father?b. How many autosomes and how many sex chromosomes are present in each somatic cell?c. How many chromosomes are present in a humanovum?d. How many sex chromosomes are present in ahuman ovum?
On rare occasions, people are born with a condition known as uniparental disomy. It happens when an individual inherits both copies of achromosome from one parent and no copies from the other parent. Thisoccurs when two abnormal gametes happen to complement each otherto produce a diploid zygote. For example, an abnormal sperm thatlacks chromosome 15 could fertilize an egg that contains two copies ofchromosome 15. In this situation, the individual has maternal uniparental disomy 15 because both copies of chromosome 15 were inheritedfrom the mother. Alternatively, an abnormal sperm with two copies ofchromosome 15 could fertilize an egg with no copies. This is known aspaternal uniparental disomy 15. If a female is born with paternal uniparental disomy 15, would you expect her to be phenotypically normal,have Angelman syndrome (AS), or have Prader-Willi syndrome(PWS)? Explain. Would you expect her to produce normal offspring oroffspring affected with AS or PWS?
Person A has a mutation in a chromosome in a liver cell, while person B has a mutation in a chromosome ina sperm cell. Explain which mutation is most likely to be harmful to the offspring of each of these individuals.
Which type(s) of cell division (mitosis, meiosis I,meiosis II) reduce(s) the chromosome number byhalf? Which type(s) of cell division can be classifiedas reductional? Which type(s) of cell division can beclassified as equational?
Pairs of chromosomes with almost identical geneticcomposition and that are found in cells of both males andfemales are calleda. sex chromosomes.b. autosomes.c. polyploid.d. chromatids.
and down syndrome the victim has an extra chromosome 21. Therefore, down syndrome is a kind of ___ and results from ___. A. aneuploidy... nondisjunction of chromosome 21 during meiosis B. polyploidy... occurrence of meiosis without cytokinesis C. translocation… insertion of a transposon into chromosome 21 D. replication air… An extra cycle of DNA synthesis during the five phase