The following diagram illustrates four genes from the genome of a certain insect. Different binding sites are labeled in the enhancer region of each gene. enhancer promoter A BC DE Gene 1 |A| Gene 2 A C D E Gene 3 A BD Gene 4 In order for a specific gene to be expressed in the insect's cells, all of the gene's binding sites must be bound by transcriptional activators. • The insect's brain cells contain activators that bind to sites A, C, D, and E • The insect's salivary gland cells contain activators that bind to sites A, B, and D Which of the following is the most likely pattern of gene expression for the insect described above? Gene 2 will be expressed in both brain and salivary gland cells Both gene 1 and gene 4 will be expressed in salivary glands, but neither will be expressed in brain cells Gene 1 will be expressed in both brain and salivary glands Both gene 2 and gene 3 will be expressed in brain cells, but neither will be expressed in salivary gland cells

The following diagram illustrates four genes from the genome of a certain insect. Different binding sites are labeled in the enhancer region of each gene. enhancer promoter A BC DE Gene 1 |A| Gene 2 A C D E Gene 3 A BD Gene 4 In order for a specific gene to be expressed in the insect's cells, all of the gene's binding sites must be bound by transcriptional activators. • The insect's brain cells contain activators that bind to sites A, C, D, and E • The insect's salivary gland cells contain activators that bind to sites A, B, and D Which of the following is the most likely pattern of gene expression for the insect described above? Gene 2 will be expressed in both brain and salivary gland cells Both gene 1 and gene 4 will be expressed in salivary glands, but neither will be expressed in brain cells Gene 1 will be expressed in both brain and salivary glands Both gene 2 and gene 3 will be expressed in brain cells, but neither will be expressed in salivary gland cells

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Description: The following diagram illustrates four genes from the genome of a certain insect. Different bindingsites are labeled in the enhancer region of each gene.enhancerpromoterABC D EGene 1ADGene 2АСDEGene 3ABDGene 4In order for a specific gene to be expre

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter16: Gene Expression

Section: Chapter Questions

Problem 14RQ: A scientist compares the promoter regions of two genes. Gene A’s core promoter plus proximal...

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3. Figure 2 illustrates how Pitx1 transcription is regulated in different tissues. The center image is that of a stickleback embryo. The drawings in the surrounding boxes show the Pitx1 gene region and activator proteins present in the jaw, pelvis, eye, or pituitary tissues. a. List all the tissues shown in Figure 2 that express the Pitx1 gene. b. If a fish does not produce activator 1 proteins because of a mutation in the gene that encodes those proteins, Pitx1 will be expressed in which of the following tissues? c. If a fish does not produce activator 3 proteins, Pitx1 will be expressed in which of the following tissues? d. A fish inherits a mutation in the Pitx1 coding region. This is a nonsense mutation that introduces a premature stop codon, resulting in a nonfunctional protein. Where would you expect Pitx1 to be expressed in this scenario?
A translocation mutation results in a silencer being inserted just upstream of the promoter of a gene (Gene X). How would you predict the expression of gene X be affected by this mutation? Gene X will not be expressed in any cell that has this mutation Gene X will not be expressed in any cell that has this mutation and the appropriate repressor protein Gene X will be expressed in any cell that has this mutation Gene X will be expressed in any cell that has this mutation and the appropriate repressor protein
For each of the terms in the left column, choose thebest matching phrase in the right column.a. basal factors 1. organizes enhancer/promoter interactionsb. repressors 2. pattern of expressiondepends on which parenttransmitted the allelec. CpG 3. activates gene transcriptiontemporal- and tissue-specificallyd. imprinting 4. site of DNA methylatione. miRNA 5. identifies DNA-binding sitesof transcription factorsf. coactivators 6. bind to enhancersg. epigenetic effect 7. bind to promotersh. insulator 8. bind to activatorsi. enhancer 9. prevents or reduces geneexpression posttranscriptionallyj. ChIP-Seq 10. heritable change in geneexpression not caused byDNA sequence mutation
An enhancer, located upstream from a gene, has the following sequence: 5′–GTAG–3′ 3′–CATC–5′ This enhancer is orientation-independent. Which of the following sequences also works as an enhancer? A. 5′–CTAC–3′ 3′–GATG–5′ B. 5′–GATG–3′ 3′–CTAC–5′ C. 5′–CATC–3′ 3′–GTAG–5′ C15.
In the regulatory switch experiment, what do you predict is a likely outcome in mice with the bat-mouse construct? Select one 1.) change in the nucleotide sequence of the Prx1 transcribed region 2.) change in the amount of Prx1 mRNA produced 3.)change in the amino acid sequence of the PRX1 protein 4.)change in the nucleotide sequence of the Prx1 mRNA produced
Although humans and nematodes (round worms) have approximately the same number of coding genes, humans exhibit greater phenotypic complexity. This illustrates the ______________________ paradox which can be partly explained by_______________________. Group of answer choices G value, differences in gene regulatory networks (e.g., # transcription factors) C-value, cell size and transposable elements G-value, cell size and transposable elements C-value, differences in gene regulatory networks (e.g., # transcription factors)
Which of the following statements is most consistent with the pattern of gene expression shown in the given graph? (A) Repressors that bind to a regulatory sequence of Gene X are present in brain tissue but not in heart tissue. (B) Gene X is located within heterochromatin in brain tissue and within euchromatin in heart tissue. (C) Small RNAs that help degrade Gene X mRNA are present in brain tissue but not in heart tissue (D)Activators that bind to an enhancer of Gene X are present in brain tissue but not in heart tissue.
Enhancers: a. are always located upstream of the TATA sequence b. are always within 200 bp of the TATA sequence c. are responsible for time and tissue specific transcription d. All the above are true.
Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription of heterochromatin (c) produce related but different proteins in different tissues (d) amplify genes to meet the requirement of high levels of a gene product (e) bind transcription factors to enhancers to activate transcription
A scientist compares the promoter regions of two genes. Gene A’s core promoter plus proximal promoter elements encompasses 70bp. Gene B’s core promoter plus proximal promoter elements encompasses 250bp. Which of the scientist’s hypotheses is most likely to be correct? More transcripts will be made from Gene B Transcription of Gene A involves fewer transcription factors Enhancers control Gene B’s transcription Transcription of Gene A is more controlled than transcription of Gene B.
Binding or ___ to ___ in DNA can increase the rate of transcription of specific genes. a. activators; repressors b. activators; enhancers c. repressors: operators d. repressors: enhancers
there is the statement: "Both stem cells and specialized cells have all the same genes. They differ in the regulation of those genes and express very different sets of genes ". Which one of the following explanations best accounts for this difference in stem cell and specialized cell gene expression? A. Stem cells and specialized cells have different activators and repressors that affect transcription B. Stem cells and specialized cells have different promoter sequences for their genes, thus affecting transcription C. Stem cells and specialized cells have different ribosomes that affect translation D. Stem cells and specialized cells use different start codons on mRNAs, thus affecting translation