The following phenylboronate is a competitive inhibitor of a chymotrypsin-like enzyme.  Unlike carbon, boron is quite happy to be bonded to three oxygens (and one carbon)—explain why this feature makes it a much better inhibitor than the corresponding carboxylic acid (which is quite ineffective).

Medical Terminology for Health Professions, Spiral bound Version (MindTap Course List)
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Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Publisher:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Chapter4: The Muscular System
Section: Chapter Questions
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The following phenylboronate is a competitive inhibitor of a chymotrypsin-like enzyme.  Unlike carbon, boron is quite happy to be bonded to three oxygens (and one carbon)—explain why this feature makes it a much better inhibitor than the corresponding carboxylic acid (which is quite ineffective).  

B
OH
OH
Transcribed Image Text:B OH OH
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