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- Three methods have been used to try to eliminate malaria. One is to eliminate the mosquito vectors of the parasite, a second is to kill the parasites after they have entered the human body, and the third is to develop a vaccine against the parasite, allowing the human immune system to provide protection from the disease. Which do you suppose is the most promising in the long run? Why? Think about both the biology of the disease and the efficacy of carrying out each of the methods on a large scale .The lack of a cure or effective treatment for malaria can be attributed to... Group of answer choices The expected return on developing a malaria vaccine is low, given the large pressure any firm would face to make such a vaccine widely available. Though Malaria is widespread, it has a very low mortality rate and has little effect on productivity Governments in malaria afflicted countries actively compete with each other to be the first to develop a malaria vaccine and this competition is counter-productive Malaria is no longer a serious issue, with very small infection ratesa. Explain the general relationships of the vector, the reservoir, andthe agent of infection. b. Can you think of an explanation for Lyme disease having such alow incidence in the southern United States? (Hint: In this region,the larval stages of the tick feed on lizards, not on mice.)
- Suppose that the health department of city A mounts a suc-cessful campaign to get children immunized against measles.Only 100 out of 10,000 children fail to receive the vaccine. Nowsuppose that city B, the same size as city A, has not carried out asuccessful measles vaccination program. Of the 10,000 childrenin city B, 5,000 had measles when the disease last struck thepopulation.(a) If a child with measles moves to city A, what is thechance that child will encounter a susceptiblechild?(b) If a child with measles moves to city B, what isthe chance that child will encounter a susceptiblechild?(c) Comparing the two scenarios, which city has thehigher herd immunity, and in which city is aninfected child more likely to transmit the diseaseto a susceptible child?According to the recent malaria report of the Department of Health, Disease and Prevention Bureau (2022), there are 4, 251 confirmed cases of malaria in the Philippines and majority of the cases are due to Plasmodium falciparum. P. falciparum life cycle includes gametocytes that will aid the parasite to reproduce sexually in its anopheline vectors. Examine Figure 2 below. Provide three (3) qualitative descriptions of the P. falciparum gametocyte. Write your answers in a complete sentence. Fig. 2.. Plasmodium falciparum gametocyte in thin blood smear (CDC, 2022)Explain why each choice (a-d) is correct or incorrect. A flu vaccine is needed seasonally to be effective but a polio vaccine is only needed once. The best explanation of this is a. Flu vaccine is substantially weaker than the polio vaccine. b. The polio virus is substantially weaker than the flu virus. c. Exposure to flu vaccine produces no memory cells from proliferating B lymphocytes. d. The flu has several strains that change seasonally.
- What is the malaria impact on global health? What are the pros/cons of the Malaria Vaccine impact?a Given these assumptions about the fifictitia epidemic, write down the two laws of motion for St and It in terms of St, It, C, p, α, β, γ , and the λs. b What conditions must be true if the populations of infected and uninfected people are in steady state (that is, they do not change over time)? c Assume γ = 0. Interpret this assumption. d Now assume γ >β. Interpret this assumption. e Assuming γ >β, solve for I∗ as a function of C, p, α, β, γ , and the λs. [Hint:As a fifirst step, you should add your two equations from part (b) to derive a relationship between I∗ and S∗.] f How does a change in the price of p affffect the steady-state level of I∗?Imagine a newly developed drug that is highly lethal against all stages in the life cycle of Toxoplasma gondii. The drug has been found to be safe and effective both for human and for veterinary use. Although the drug can eliminate infection in both humans and cats, its use in humans will have vey little impact on overall prevalence of human toxoplasmosis. Its use in cats, alternatively, could, at least in theory, reduce prevalence in both humans and cats. Explain this difference.
- Assuming you have been posted to a community where malaria is very endemic. There is a high rate of absenteeism among your students due to incidents of malaria. As part of your community engagement explain how you would educate on malaria prevention taking the following into consideration:a) Name of the vector and the species of the parasite that cause the diseases in Africa; b) Two chemical and two biological ways of reducing the population of mosquitoes; c) Two in-house measures to prevent mosquitoes bite;d) The stages in the life cycle of the mosquito;e) The names of three African countries that participated in the trial of malarial vaccine.The book "Spillover" by David Quammen mentions the significance of anecdotal evidence from locals who've experienced isolated outbreaks. Give an example from the book of such evidence and how it is actually valuable to scientists, even if accounts are second- or third hand. How was anecdotal evidence used to understand the spread of the COVID-19 pandemic? Give two specific examples.H1N1 infl uenza has been the cause of four pandemics in recent history: 1918, 1957, 1968, and 2009. How is it possible to have multiple H1N1 pandemics in the same century?