The    LD50(mice)    for    caffeine    is    192    mg/kg,    and    for    nicotine    it    is    0.75mg/kg.    Assuming    the    LD50for    humans    is    similar    to    that    measured    for    mice    (or    that    you    have    a    mouse    the    size    of    an    average    adult    weighing    154    lb),    determine    the    number    of    grams    of    caffeine    and    nicotine    that    would    be    lethal    to    50%    of    the   human    (giant    mouse)

Chemistry In Focus
7th Edition
ISBN:9781337399692
Author:Tro, Nivaldo J.
Publisher:Tro, Nivaldo J.
Chapter17: Drugs And Medicine: Healing, Helping, And Hurting
Section: Chapter Questions
Problem 68E
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The    toxicity    of    a    compound    is    often    reported    as    the    LD50,    which    is    the    lethal    dose    for    50%    of    a    population.    The    LD50is    typically    measured    using    mice    and    is    reported    in    units    of    milligrams    of    the    compound    per    kilogram    of    the    body    mass    of   the    population.    The    LD50(mice)    for    caffeine    is    192    mg/kg,    and    for    nicotine    it    is    0.75mg/kg.    Assuming    the    LD50for    humans    is    similar    to    that    measured    for    mice    (or    that    you    have    a    mouse    the    size    of    an    average    adult    weighing    154    lb),    determine    the    number    of    grams    of    caffeine    and    nicotine    that    would    be    lethal    to    50%    of    the   human    (giant    mouse)

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