The partial pressure and solubility of a substance plays a very important role in human physiology, especially for oxygen. This becomes especially important when an individual has an illness or condition that affects the amount of oxygen available for circulating to the human body. Recall that the solubility of oxygen in blood (a) for healthy individuals is ~ 2e-3 cm³ O2/cm³ / mmHg, and that the typical partial pressure of oxygen (P) in blood is 100 mmHg. This is for a patient with a blood hematocrit of 42%, i.e., hemoglobin of 140 g/L 1. Case 1: A patient has low blood cell count (hence low hematocrit), and his hematocrit has reduced by 25%. Estimate how much oxygen is available in his blood? Assume a linear relationship between hematocrit and solubility. 2. Case 2: A patient has normal blood hematocrit, but a lung disease that reduces her partial pressure of oxygen to 60 mmHg. What happens to the oxygen in her blood? 3. Case 3: A patient has normal blood oxygen partial pressure and normal hematocrit, but oxygen saturation is 20%. How does this affect the oxygen available to him?
The partial pressure and solubility of a substance plays a very important role in human physiology, especially for oxygen. This becomes especially important when an individual has an illness or condition that affects the amount of oxygen available for circulating to the human body. Recall that the solubility of oxygen in blood (a) for healthy individuals is ~ 2e-3 cm³ O2/cm³ / mmHg, and that the typical partial pressure of oxygen (P) in blood is 100 mmHg. This is for a patient with a blood hematocrit of 42%, i.e., hemoglobin of 140 g/L 1. Case 1: A patient has low blood cell count (hence low hematocrit), and his hematocrit has reduced by 25%. Estimate how much oxygen is available in his blood? Assume a linear relationship between hematocrit and solubility. 2. Case 2: A patient has normal blood hematocrit, but a lung disease that reduces her partial pressure of oxygen to 60 mmHg. What happens to the oxygen in her blood? 3. Case 3: A patient has normal blood oxygen partial pressure and normal hematocrit, but oxygen saturation is 20%. How does this affect the oxygen available to him?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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![The partial pressure and solubility of a substance plays a very important role in human
physiology, especially for oxygen. This becomes especially important when an individual has an
illness or condition that affects the amount of oxygen available for circulating to the human
body. Recall that the solubility of oxygen in blood (a) for healthy individuals is ~ 2e-3 cm³
O2/cm³ / mmHg, and that the typical partial pressure of oxygen (P) in blood is 100 mmHg. This
is for a patient with a blood hematocrit of 42%, i.e., hemoglobin of 140 g/L
1. Case 1: A patient has low blood cell count (hence low hematocrit), and his hematocrit has
reduced by 25%. Estimate how much oxygen is available in his blood? Assume a linear
relationship between hematocrit and solubility.
2. Case 2: A patient has normal blood hematocrit, but a lung disease that reduces her partial
pressure of oxygen to 60 mmHg. What happens to the oxygen in her blood?
3. Case 3: A patient has normal blood oxygen partial pressure and normal hematocrit, but
oxygen saturation is 20%. How does this affect the oxygen available to him?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F0c76fac4-28ed-4648-9f54-320c35767717%2F94fcc30f-db47-451f-871d-d22a990811ec%2F95odsap_processed.png&w=3840&q=75)
Transcribed Image Text:The partial pressure and solubility of a substance plays a very important role in human
physiology, especially for oxygen. This becomes especially important when an individual has an
illness or condition that affects the amount of oxygen available for circulating to the human
body. Recall that the solubility of oxygen in blood (a) for healthy individuals is ~ 2e-3 cm³
O2/cm³ / mmHg, and that the typical partial pressure of oxygen (P) in blood is 100 mmHg. This
is for a patient with a blood hematocrit of 42%, i.e., hemoglobin of 140 g/L
1. Case 1: A patient has low blood cell count (hence low hematocrit), and his hematocrit has
reduced by 25%. Estimate how much oxygen is available in his blood? Assume a linear
relationship between hematocrit and solubility.
2. Case 2: A patient has normal blood hematocrit, but a lung disease that reduces her partial
pressure of oxygen to 60 mmHg. What happens to the oxygen in her blood?
3. Case 3: A patient has normal blood oxygen partial pressure and normal hematocrit, but
oxygen saturation is 20%. How does this affect the oxygen available to him?
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