The pKa of hydroxyl a on the compound is 7.15, while the pKa of hydroxyl b is 9.3. What key resonance structure explains that difference?

Q: The purine heterocycle occurs commonly in the structure of DNA.a.How is each N atom hybridized? b.In…

A: a.

Q: Explain this result: Acetic acid (CH3COOH), labeled at its OH oxygen with the uncommon 18O isotope…

A:

Q: Without using the pKa, write the reaction scheme then decide which direction the reaction be…

A: First we will see the product of this equilibrium reaction.  When two ammonia molecules reacting to…

Q: One of the heptanedione isomers below has a pka of approximately 9 rather than 20. Which isomer?…

A:

Q: What is each compound’s systematic name?

A: The given compound is shown below,

Q: Which of the following substituents is ortho/para directing and deactivating in electrophilic…

A: We have to choose substituents  that is ortho/para directing and deactivating in electrophilic…

Q: B. Which SN1 reaction of each pair would you expect to take place more rapidly? Explain your answer.…

A: SN1 reaction is the unimolecular nucleophilic substitution reaction in which the nucleophile…

Q: Which of these radicals has another resonance contributor?

A: In order to find resonance contributor radical, we need to check conjugation

Q: What is each compound’s systematic name?

A: The given compound is a tertiary amine with two methyl groups and one cyclohexyl group. The IUPAC…

Q: Give the structure of compound A

A: The given reaction is a Friedel Crafts alkylation reaction. The reaction between arenes and acyl…

Q: Propose a structure for this dianion and suggest why it forms so rea

A:

Q: НО :0:

A: Rp

Q: What are the major resonance contributors for the amine, there are four more

A:

Q: Which is more stable: aromatic or aliphatic diazonium salts? Motivate.

A: Diazo group attached to aromatic ring is known as aromatic diazonium salt and the diazo group…

Q: Draw all possible resonance structures for the antihistamine diphenhydramine, the active ingredient…

A: Structure of diphenhydramine :

Q: Why a nitro group (NO2) directs electrophilic aromatic substitution tothe meta position ?

A: Electrophilic aromatic substitution is the reaction in which an atom attached to the aromatic ring…

Q: Prontosil, an azo dye, is a prodrug. It is metabolized in the body to the sulfa drug sulfanilamide,…

A:

Q: Draw all possible resonance structures for the antihistamine diphenhydramine, the active ingredient…

A:

Q: Stanozolol is an anabolic steroid that promotes muscle growth. Although stanozolol has been used by…

A: Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…

Q: Draw all possible resonance structures for the antihistamine diphenhydramine, the active ingredient…

A:

Q: Electrophilic aromatic substitution involves a cationic intermediate in which positive charge is…

A: Mechanism is given below

Q: Stanozolol is an anabolic steroid that promotes muscle growth. Although stanozolol has been used by…

A: a)  The pyrazole ring in the given molecule Stanozolol is aromatic because of the continuous…

Q: Consider the tetracyclic aromatic compound drawn below, with rings labeled as A, B, C, and D. (a)…

A: The compound is

Q: How would you explain the o-p directing formation of phenol, while nitro benzene is m directional?…

A: By drawing resonating strutures of phenol and nitrobenzene we can explain their directing behaviour.

Q: Explain why aromatic protons resonate downfield and aliphatic resonate upfield.

A: In NMR spectroscopy,

Q: Which of the following should be stabilized by resonance and why?

A: Aromatic compounds are those which has (4n+2)π electron system i.e. follows Huckel rule.  planar…

Q: Which is a resonance contributor for this molecule? :ö:

A: Resonance is delocalization of electrons.

Q: Azulene, an isomer of naphthalene, has a remarkably large dipole moment for a hydrocarbon (µ = 1.0…

A:

Q: Write an additional resonance contributing structure for each carbocation and state which of the two…

A: The generation of polarity in a molecule because of interaction of the lone pair and pi-bond that…

Q: Draw all resonance structures of the conjugate bases formed by removal of the labeled protons (Ha,…

A: On removing the hydrogen Ha from acetanilide, the conjugate base formed does not exhibits the…

Q: Pyridine and pyrrole, which is more basic and why? H. pyridine pyrrole • A - Pyrrole, protonation…

A:

Q: Which of the following ions is aromatic? 0000 B

A:

Q: Both pyrrole and pyridine are nitrogen containing heterocycles that are 6π Hückel aromatic. Describe…

A: Greater the percentage S character less will be the ability of donation of electron and hence less…

Q: Rosmarinic acid is an antioxidant isolated from rosemary. Draw resonance structures for the radical…

A: The removal of hydrogen atom in rosmarinic acid results in the formation of radical as shown below,

Q: Compare the resonance energy of biphenyl with that of naphthalene and with that of two benzene…

A: The resonance energy for biphenyl is 302 kJ/mol while the resonance energy for naphthalene is 255.2…

Q: 10 Discuss the aromaticity of the below compounds? Explain which compound is aromatic, why?

A:

Q: The purine heterocycle occurs commonly in the structure of DNA. How is each N atom hybridized?

A: Hybridization: When atomic orbitals combine together, resulting in the formation of a new…

Q: Q2. Rank the following benzoic acid derivatives in order of their pk, values, and explain your…

A: Now, Here on benzoic acid 2 substituents are attached NH2 and NO2. NH2 is electron donating in…

Q: Which of the following resonance structures is the greatest contributor to the resonance hybrid? O:

A:

Q: A bicyclic heterocycle aromatic ring with one N atom and the rings are of different size.   a…

A: A bicyclic heterocycle aromatic ring with one N atom and the rings are of different size

Q: The purine heterocycle occurs commonly in the structure of DNA. Why is purine aromatic?

A: Why purine is aromatic to be explained?

Q: Which of the following should be stabilized by resonance and why ?

A: The given compound has two cyclic rings attached by single bonds. The compound will show resonance…

Q: When enamine A is reacted with methylbromide (CH3-Br) two products B and C can form. Br B H3C-Br CH3…

A: Enamine gives nucleophilic substitution reactions with alkyl halides.

Q: Purine is a heterocyclic compound with four nitrogen atoms. a. Which nitrogen is most apt to be…

A: (a) In purine compound, four nitrogen atoms are present and all are sp hybridized nitrogen atoms.…

Q: Draw both resonance structures of the anion formed by the reaction of the most acidic C-H bond of…

A: The acidic hydrogen will be the hydrogen of the compound which can be removed easily, or in other…

Q: How would you explain the o-p directing formation of phenol, while nitro benzene is m-directional?…

A: Explained as follows

Q: Which of the following lone pairs of purine participate in its aromaticity? N. C

A: