The practical limit for the number of different RNA sequences screened in a SELEX experiment is 10¹5. Suppose you are working with oligonucleotides 36 nucleotides long. How many sequences exist in a randomized pool containing every sequence possible? total number of sequences: What percentage of these can a SELEX experiment screen? percentage of RNA molecules screened in SELEX experiment: Suppose you wish to select an RNA molecule that catalyzes the hydrolysis of a particular ester. From what you know about catalysis, which SELEX strategy might allow you to select the appropriate catalyst?

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter19: Genomes And Proteomes
Section: Chapter Questions
Problem 1ITD: Below is a sequence of 540 bases from a genome. What information would you use to find the...
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The practical limit for the number of different RNA sequences screened in a SELEX experiment is 10¹5. Suppose you are
working with oligonucleotides 36 nucleotides long.
How many sequences exist in a randomized pool containing every sequence possible?
total number of sequences:
What percentage of these can a SELEX experiment screen?
percentage of RNA molecules screened in SELEX experiment:
Suppose you wish to select an RNA molecule that catalyzes the hydrolysis of a particular ester.
From what you know about catalysis, which SELEX strategy might allow you to select the appropriate catalyst?
%
Transcribed Image Text:The practical limit for the number of different RNA sequences screened in a SELEX experiment is 10¹5. Suppose you are working with oligonucleotides 36 nucleotides long. How many sequences exist in a randomized pool containing every sequence possible? total number of sequences: What percentage of these can a SELEX experiment screen? percentage of RNA molecules screened in SELEX experiment: Suppose you wish to select an RNA molecule that catalyzes the hydrolysis of a particular ester. From what you know about catalysis, which SELEX strategy might allow you to select the appropriate catalyst? %
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