The steep part of the O2-Hb dissociation curve... a. is where CO2 unloading occurs at the tissue cells b. is where the PO2 is high (>90mmHg) c. is where the oxyhemoglobin is high (>90 % saturated) d. is where O2 unloading occurs at the tissue cells
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The steep part of the O2-Hb dissociation curve...
is where CO2 unloading occurs at the tissue cells
is where the PO2 is high (>90mmHg)
is where the oxyhemoglobin is high (>90 % saturated)
is where O2 unloading occurs at the tissue cells
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- Which of the following statements about the oxygen-binding curves is FALSE? Select one: a. During normal activity (not exercising) the blood PO2 rarely falls below 40 mmHg. b. The PO2 and hemoglobin dissociation curve for myoglobin is to the left of fetal hemoglobin. c. The blood returning to the lungs is still 75% saturated with oxygen. d. A larger decrease in PO2 is needed for hemoglobin to drop from 100% to 75% O2 capacity than from 75% to 50% O2 capacity. e. During high metabolic activity the PO2 and hemoglobin dissociation curve would be expected to shift to the left of normal.The oxyhemoglobin dissociation (saturation) curve shifts to the right as the blood becomes more acidic. Under these conditions answer the following. At a P O2 = 40 mmHg the percent saturation of hemoglobin __________ and the content of oxygen bound to hemoglobin ____________. A. Decreases; decreases B. Increases; increases C. Increases; decreases D. Decreases; increases E. Does not change; does not changeWhile a runner rests before a race, the hemoglobin in the blood returning to her heart is 75% saturated with O2 (that is, the blood is carrying about 75% of the maximum possible capacity to carry O2). While she is running, this percentage ... A. decreases because the partial pressure of O2 in her lung alveoli is reduced to below 40 mm Hg. B. decreases because the decreased PO2 in her muscles promotes O2 unloading in those tissues. C. stays the same because hemoglobin is usually 75% saturated with O2. D. increases because her muscles need more O2. E. increases because she is breathing harder.
- During respiration, oxygen is inhaled through the airways into the alveoli where gas exchange occurs. For each condition described below, state if the flux of oxygen through the blood gas barrier into the pulmonary capillaries increases or decreases. Use Fick’s law to justify your answer. a. Climbing to the top of Mt. Everest b. More abundant but smaller alveoli c. Extreme increase in pulmonary capillary pressure d. Pulmonary fibrosisWhat is the biological advantage to the sigmoidal binding curve of hemoglobin for oxygen? A. It ensures that hemoglobin has a high affinity for oxygen. B. It allows hemoglobin to bind oxygen irreversibly. C. It ensures that hemoglobin can bind oxygen only weakly. D. It allows hemoglobin to shift between low and high affinities for oxygen.The partial pressure of oxygen in the venous blood of a human at rest at sea level is approximately 40 torrs a.) Calculate the fractional saturation of hemoglobin under these conditionsb.) What percentage of the oxygen originally bound to hemoglobin in the alveoli remained unreleased?c.) Is the residual oxygen bound to hemoglobin under these conditions of any benefit? Explain
- Which of the following factors would NOT increase the rate of diffusion of oxygen through the respiratory membrane? A) Increasing the SA/V ratio B) Increasing the partial pressures C) Decreasing the surface area D) Decreasing the thickness of the membrane E) Decreasing the distance the gas has to diffuseWith rare exceptions, the majority of oxygen is transported in the bloodof vertebratesa. by binding to plasma proteins.b. by binding to hemoglobin in erythrocytes.c. as dissolved gas in the plasma.d. as dissolved gas in the cytoplasm in the erythrocytes.e. by binding to myoglobin.When we change altitude, during the next few days, the body responds by adjusting Hb cooperativity. This can be accomplished by changing the concentration of 2,3-BPG in the blood. After moving from a low altitude to a higher altitude, does 2,3,-BPG increase or decrease? Explain how this affects oxygen transport capacity
- Explain why the gas values from the alveolar air to the blood change during pulmonary gas exchange. For example: Alveolar air for CO2 has a value of 40mmHg then when entering the blood shifts to 45mmHg. Why does this occur? I tried to calculate this by using Dalton’s law but I’m not Understanding.Which of the following concerning hemoglobin is true? a) BPG decreases at high altitudes and causes more O2 offloading in tissues b) As pH increases, [CO2] increases in tissues, causing more O2 release in tissue c) The R state is stabilized by CO2 binding, whereas the T state is stabilized by O2 binding d) About 38% of oxygen dissociates from hemoglobin in tissues e) Hemoglobin has a higher affinity for oxygen than carbon monoxide My guess is D.Which of the following concerning hemoglobin is true? a) BPG decreases at high altitudes and causes more O2 offloading in tissues b) As pH increases, [CO2] increases in tissues, causing more O2 release in tissue c) The R state is stabilized by CO2 binding, whereas the T state is stabilized by O2 binding d) About 38% of oxygen dissociates from hemoglobin in tissues e) Hemoglobin has a higher affinity for oxygen than carbon monoxide My guess is D. What following statement is TRUE concerning motifs and domains? a) Both motifs and domains are independently stable. b) Domains undergo dynamic individual changes that affect the entire protein c) B-a-ß loops, B barrels, and helix-turn-helix structure are types of domains d) Motifs and domains are part of secondary structural elements e) Ab initio computations predict motif folds accurately a majority of the time My guess is B. Which of the following is TRUE under the following conditions: an enzyme displaying Michaelis-Menten kinetics…