The time is coming when choosing the genetic traits of your child is going to be possible. What kinds of ethical and practical problems may arise from this development?
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The time is coming when choosing the genetic traits of your child is going to be possible. What kinds of ethical and practical problems may arise from this development?
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- As a physician, you deliver a baby with protruding heels and clenched fists with the second and fifth fingers over-lapping the third and fourth fingers. a. What genetic disorder do you suspect the baby has? b. How do you confirm your suspicion?If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this an indication that there is a genetic contribution to these traits? What would you do to confirm that genetics is involved in this condition?Jan is concerned about using ART. She wants to be the genetic mother and have Darryl be the genetic father of any children they have. What methods of ART would you recommend to this couple? Jan, a 32-year-old woman, and her husband, Darryl, have been married for 7 years. They have attempted to have a baby on several occasions. Five years ago, they had a first-trimester miscarriage, followed by an ectopic pregnancy later the same year. Jan continued to see her OB/GYN physician for infertility problems but was very dissatisfied with the response. After four miscarriages, she went to see a fertility specialist, who diagnosed her with severe endometriosis and polycystic ovarian disease (detected by hormone studies). The infertility physician explained that these two conditions were hampering her ability to become pregnant and thus making her infertile. She referred Jan to a genetic counselor. At the appointment, the counselor explained to Jan that one form of endometriosis (MIM 131200) can be a genetic disorder, and that polycystic ovarian disease can also be a genetic disorder (MIM 184700) and is one of the most common reproductive disorders among women. The counselor recommended that a detailed family history of both Jan and Darryl would help establish whether Jans problems have a genetic component and whether any of her potential daughters would be at risk for one or both of these disorders. In the meantime, Jan is taking hormones, and she and Darryl are considering alternative modes of reproduction. Using the information in Figure 16.4, explain the reproductive options that are open to Jan and Darryl.
- In the future, gene technology may make it possible for parents to produce children with athletic ability, artistic talent, or high IQ. Do you have any ethical concerns about these possibilities? If so, where and how would you draw the line?Why shouldn't genetic testing be mandatory for those planning on having children?Create a hypothetical person and situation as a real life example to illustrate your position. Who is this person? How old is this person? What chromosomal abnormalities does this person have? How does genetic testing and counseling make this person’s life better or worse? Ultimately, should your hypothetical person seek genetic counseling?
- If a man has an X-linked recessive disease, can his sons inherit that disease from him? Why or why not?Would you use gene therapy to enhance your basic traits such as height, intelligence and athletic ability? Why or why not?Amy Alvarez had a recessive X-linked chromosome for a disorder such as, hemophilia, and said that she wanted to have all boys because they would not show symptoms? Would she be well informed?
- Suppose you are a carrier of fragile X syndrome and want to have children. Would you choose pregnancy, adoption, or surrogacy? If you became pregnant, would you opt for prenatal diagnosis? Explain your decisions.A color-blind woman and a man with normal color vision have three sons and six daughters. All the sons are color blind. Five of the daughters have normal color vision, but one of them is color blind. The color-blind daughter is 16 years old, is short for her age, and has not undergone puberty. Explain how this girl inherited her color blindness.Alex is newly pregnant with twins and curious about everything about her developing children. Her doctor was able to tell her that her twins are dizygotic twins via ultrasound. In your essay, describe the difference between monozygotic and dizygotic twins and explain how each is conceived. Alex is also wondering about the genetics of her children and how they will act when they are older. Offer an explanation of genotype and phenotype and provide an example of each specific to Alex’s future children being dizygotic twins. Finally, in your previous explanation be sure to also describe how most traits are both polygenic and multifactorial and how that may influence her twins’ phenotypes.