There are two alleles for the arr gene, A and a. There are also two alleles for bee gene, B and b. The two genes are on a chromosome that is 1.5 micrometers in length, but it has yet to be determined if the two genes are linked. Below is data from a study to determine if the genes are linked, and if so, how far apart the genes are on the chromosome.

Algebra & Trigonometry with Analytic Geometry
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ISBN:9781133382119
Author:Swokowski
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Chapter10: Sequences, Series, And Probability
Section10.8: Probability
Problem 32E
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Question 9: FOR THIS QUESTION, EXCEL *MUST* BE USED TO CALCULATE THE P-VALUE FOR CHI SQUARED!

Can you answer all the parts to this question, with clearly showing which part you're answering and make sure to round accordingly. 

There are two alleles for the arr gene, A and a. There are also two alleles for bee gene, B
and b. The two genes are on a chromosome that is 1.5 micrometers in length, but it has yet
to be determined if the two genes are linked. Below is data from a study to determine if the
genes are linked, and if so, how far apart the genes are on the chromosome.
An organism that is heterozygous for both the arr gene and the bee gene is crossed with an organism
that is homozygous recessive for both genes.
Using this information, it is possible to calculate the expected phenotypic ratio of the offspring of the two organisms,
assuming the two genes are *NOT* linked. If the genes are linked, the offspring will not exhibit the expected
phenotypic ratio.
1. The arr and bee genes are independent of each other.
2. The arr and bee genes are linked.
Above are the two hypotheses. Which of the two hypotheses is the null hypothesis?
Enter either 1 or 2 in the answer box
The table below depicts the observed genotypic abundances of the offspring.
Genotype Abundance
Аа Bb
47
Aa bb
23
aа Bb
31
aa bb
39
Use the predicted and observed data to perform a chi-squared test to assess if two genes arr and bee are linked.
Below is a video about how to perform the calculations in Excel.
Transcribed Image Text:There are two alleles for the arr gene, A and a. There are also two alleles for bee gene, B and b. The two genes are on a chromosome that is 1.5 micrometers in length, but it has yet to be determined if the two genes are linked. Below is data from a study to determine if the genes are linked, and if so, how far apart the genes are on the chromosome. An organism that is heterozygous for both the arr gene and the bee gene is crossed with an organism that is homozygous recessive for both genes. Using this information, it is possible to calculate the expected phenotypic ratio of the offspring of the two organisms, assuming the two genes are *NOT* linked. If the genes are linked, the offspring will not exhibit the expected phenotypic ratio. 1. The arr and bee genes are independent of each other. 2. The arr and bee genes are linked. Above are the two hypotheses. Which of the two hypotheses is the null hypothesis? Enter either 1 or 2 in the answer box The table below depicts the observed genotypic abundances of the offspring. Genotype Abundance Аа Bb 47 Aa bb 23 aа Bb 31 aa bb 39 Use the predicted and observed data to perform a chi-squared test to assess if two genes arr and bee are linked. Below is a video about how to perform the calculations in Excel.
What is your calculated value of chi squared?
• Report your answer to FOUR decimal places
FURTHER CALCULATIONS SHOULD BE PERFORMED IN EXCEL ON THE UNROUNDED NUMBER
What is the P-value determined using the formula =(1-chisq.dist(x, df, TRUE) in Excel, where x is the calculated value
of chi squared, df is the degrees of freedom, and TRUE indicates a cumulative distribution function.
• Report your answer to FOUR decimal places
Using an alpha value of 0.05, do you fail to reject or reject the null hypothesis?
Enter either fail to reject, or reject.
If the genes are linked, use the percent of offspring that experienced crossing over to determine the distance between
the two genes in micrometers. If the genes are not linked, enter n/a in the box below
micrometers
• Report your answer in micrometers
• Report your answer to four decimal places
• Or enter n/a if the genes are not linked
Transcribed Image Text:What is your calculated value of chi squared? • Report your answer to FOUR decimal places FURTHER CALCULATIONS SHOULD BE PERFORMED IN EXCEL ON THE UNROUNDED NUMBER What is the P-value determined using the formula =(1-chisq.dist(x, df, TRUE) in Excel, where x is the calculated value of chi squared, df is the degrees of freedom, and TRUE indicates a cumulative distribution function. • Report your answer to FOUR decimal places Using an alpha value of 0.05, do you fail to reject or reject the null hypothesis? Enter either fail to reject, or reject. If the genes are linked, use the percent of offspring that experienced crossing over to determine the distance between the two genes in micrometers. If the genes are not linked, enter n/a in the box below micrometers • Report your answer in micrometers • Report your answer to four decimal places • Or enter n/a if the genes are not linked
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