Two phenotypically normal parents produce an abnormal son in which chromosome 14 ismissing part of its short arm but has a piece of chromosome 21 attached to it. The child alsohas one normal copy of chromosome 14 and two normal copies of chromosome 21.(i)With regard to chromosome 14 and 21, what do you think are the chromosomalcompositions of the parent?(ii)Draw the pairing of the translocated chromosomes in the parent during meiosis andname the segregation pattern that contributes to the abnormal karyotype.(iii)State the syndrome and write the notation for this child's karyotype.

Translocations are chromosomal rearrangements caused by the exchange of components between two…

Answered: Two phenotypically normal parents…

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 3CT: People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes....

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Similar questions

People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes. However, in a few cases of Down syndrome, 46 chromosomes are present. This total includes two normal-looking chromosomes 21, one normal chromosome 14, and a longer-than-normal chromosome 14. Interpret this observation. How can these individuals have 46 chromosomes?
Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?
We are following the progress of human chromosome 1 during meiosis. At the end of prophase I, how many chromosomes, chromatids, and centromeres are present to ensure that chromosome 1 faithfully traverses meiosis?
Two phenotypically normal parents produce a phenotypicallyabnormal child in which chromosome 5 is missing part of its longarm but has a piece of chromosome 7 attached to it. The child alsohas one normal copy of chromosome 5 and two normal copies ofchromosome 7. With regard to chromosomes 5 and 7, what do youthink are the chromosomal compositions of the parents?
A woman with an abnormally long chromosome 13 (and a normalhomolog of chromosome 13) has children with a man with anabnormally short chromosome 11 (and a normal homolog of chromosome 11). What is the probability of producing an offspringthat will have both a long chromosome 13 and a short chromosome11? If such a child is produced, what is the probability that thischild will eventually pass both abnormal chromosomes to one ofhis or her offspring?
Two phenotypically unaffected parents produce two children withfamilial Down syndrome. With regard to chromosomes 14 and 21,what are the chromosomal compositions of the parents?
What are chromosome 9 characteristics and where does chromosome 9 represent?
A phenotypically normal woman has an abnormally structured chromosome 2, along with a normal homologue. She marries a phenotypically normal man with an abnormally structured chromosome 16 and a normal homologue. What is the probability of their child will have an abnormal chromosome 2 and 16? What is the probability that this child, having inherited both abnormal chromosomes, will now pass both abnormal chromosomes to its children?
If there are 9 chromosome pairs, how many univalents are there at anaphase I on each pole?
Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?
A man who is a carrier of a translocated 15/21 chromosome marries a genotypically normal woman. (1). Show the possible gametes that will be formed by this man if the translocated 15/21 chromosome synapses with chromosome 21 at Prophase I. (2). What is the probability that the first child of the couple will be a phenotypically normal girl? (3). What is the probability that the first child of the couple will be a genetically normal boy?
Two phenotypically normal parents produce a phenotypically abnormal child in which chromosome 5 is missing part of its long arm but has a piece of chromosome 7 attached to it. The child also has one normal copy of chromosome 5 and two normal copies of chromosome 7. With regard to chromosomes 5 and 7, what do you think are the chromosomal compositions of the parents? Would it most likely be reciprocal translocation? It wouldn't be simple translocation because then the child would have the entirety of one chromosome and only some of the other, but in this case, there is only partial chromosome 5 and chromosome 7?

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