Use these pka values to calculate the charge on the peptide below at pH 6. alpha COOH 2.0 side Chain COOH 4.4 His 7.0 Tyr 10.0 alpha amino 9.0 Lys 10 Arg 12 Cys 8 ISYMCFHKWGPRIE The charge on this peptide at pH 6 is and the pl of the peptide is What are the charge and isoelectric point (PI) of the peptide above at pH 6. The pKa's for each side chain has been provided above (picture).
Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
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