What are the possible causes of variations? Give specific examples.

Q: How to Calculate the Lod score numerator?

A: LOD stands for “logarithm of the odds.” It is a statistical tool used to estimate whether two genes…

Q: What happens during duplication?

A: Mutations are defined as the permanent change in the DNA’s base sequence. An agent that causes…

Q: Differentiate between D-value and z-value.

A: Introduction  Sterilization is the process of completely eliminating or destroying all microbial…

Q: describe what is CNVCopy number variant?

A: The human genome consists of 6 billion chemical bases or nucleotides of DNA packed into two sets of…

Q: How we can know the rare inherited genetic disorders by the incidence ? Explain

A: Inheritance is the process of transmitting the traits from parent to offspring. Traits of an…

Q: Several Types of Genetic Variants Occur?

A: Genetic variation is phenomenon of change in the DNA sequence of genome in a constraint individual…

Q: What is the basis for spectrum karyotyping?

A: Answer: Introduction:  A karyotype is the method of taking picture of chromosomes and to study its…

Q: How to detect a loss of heterozygosity?

A: Step 1 The loss of heterozygosity (LOH) can also be a cross chromosome phenomenon. The loss of…

Q: What is a complementation test and what is it used for?

A: Gene is a functional unit of hereditary, its expression plays a vital role in determining the…

Q: describe some of the human genetic disorders that are caused by nondisjunction?

A: Step 1 Nondisjunction is the non separation of homologous chromosomes during anaphase I that brings…

Q: Explain the concept of genomic variation ?

A: Genomic variation is the change or slight difference in condition or amount level, with certain…

Q: what is dosage compensation.?

A: Sex of an organism in various species depends on the type and number of sex chromosomes. In species…

Q: Define what is the Karyotype ?

A: The process in which the chromosomes of an organism are paired and ordered is known as Karyotyping.…

Q: How many genetic diseases can we identify using DNA testing?

A: Genetic testing or DNA testing is done to identify errors or changes occurred in a DNA sequence or…

Q: What is the effect of inversion mutation?

A: Mutation is a change in the sequence of genetic material either due to the mistake in replication or…

Q: What is the diagnostic test for linkage?

A: Chromosomes are the condensed form of DNA that carry all the genes.  Genes are represented in the…

Q: What does red list contains?

A: The international union for conservation of nature (IUCN) is an international organization that…

Q: Define inversions

A: The variations in the chromosome structure arises because of the following four processes :…

Q: How common is dup15q?

A: Dup15q:- Is characterized by having an extra copy of a portion  of chromosome 15[partial trisomy] in…

Q: Explain the Syndromes from AbnormalChromosome Numbers ?

A: Chromosomes are thread-like structures present inside the nucleus of the cell. They are made up of…

Q: What is a molecular marker? Elaborate physical chromosome mapping with the help of molecular markers

A: Molecular mapping is used to find the location of gene on the chromosome and also the distance…

Q: What is a complementation test?

A: Genetics is the branch of Biology dealing with the study of genes including their structure,…

Q: How can Cri-Du-Chat syndrome be diagnose with karyotyping?

A: Karyotyping is a genome-wide snapshot of an individual's chromosomes. It's a collection of a cells…

Q: What is spectral karyotype ?

A: Introduction:- Karyotyping is a test that looks at the chromosomes of a group of cells. This test…

Q: Distinguish between pericentric and paracentric inversions.

A: Inversion is when a piece of a chromosome is broken and it is arranged after inverting it.

Q: physical appearances of individuals affected by the abnormality structure of deletion, inversion,…

A: The phenotypes of individuals are effected by numerous factors. As much as it depends on factors…

Q: What are factors that alter the phenotypic expression of genotype?

A: Genotype The genotype can be defined as the genetic make-up of an individual organism. Our genotype…

Q: What are the possible causes of genetic variations? Give specific examples.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Briefly describe polymorphism?

A: Morphism is the development of a particular phenotype in an organism. Organisms have many sets of…

Q: How are karyotypes used?

A: Karyotype is the collection of chromosomes which is examined for certain purposes. Chromosomes…

Q: Which individuals can be termed as clones?

A: DNA is the genetic material in most living organisms. It is the information hub that contains…

Q: Define common variants

A: A common variant is a part of a hypothesis "Common diseases-common variant" that accounts for the…

Q: Differentiate between parental ditype (PD), nonparental ditype (NPD), and tetra type (T).

A: The spores are the meiotic products of a yeast. They remain packed in the parent cell to form a…

Q: r rr rr Which best describes the parent genotypes in the punnet square provided?

A: Genetic inheritance is the passage of genetic information or Genetic character from the parents to…

Q: determining coat color is the agouti gene?

A: The coloration, pattern, and length of the cat fur is governed by numerous genes and is determined…

Q: List the three basic categories of chromosome mutations and define each one.

A: Aneuploidy refers to a condition of an abnormal or unusual number of chromosomes. Normally each…

Q: Explain the Categories of Genetic Variants?

A: Genetics is the study of how traits are passed from one generation to another. This includes but is…

Q: What types of chromosomal disorders are easily seen with a karyotype?

A: KARYOTYPE:- It is the complete set of chromosomes of an individual used to check for any…

Q: What is the Philadelphia chromosome? How is this chromosome related to cancer? Identify how this…

A: A chromosome could be a dna (deoxyribonucleic acid) molecule with some  or all of the genetic…

Q: Indicate how D-value and z-value differ.

A: Introduction A microbe, or microorganism, is a microscopic organism. It may occur as a single-celled…

Q: The karyotypes shown here depict chromosomal abnormalities. Name the syndromes and if they are male…

A: "Genes" are the fundamental unit of heredity. They store genetic information in the form of DNA,…

Q: Are changes that cause high FST found equally across the genome? What areas of the genome would be…

A: The fixation index is a measure of the population difference due to the genetic structure. It is the…

Q: Explain dosage compensation?

A: It is a mechanism that helps in maintaining the number of X chromosomes by inactivating 1 X…

Q: Explain the term pleiotropy.

A: Genes are the basic structural and functional unit of heredity. They carry coded genetic information…

Q: Compare and contrast the molecular mechanisms leading to FX syndrome and to FSHMD.

A: Introduction :- A gene originally known as FMR1 gene by scientists and responsible for FXS is…

Q: give an example of inversion?

A: An Inversion is a abnormal chromosomal rearrangement in which chromosomal segments are reversed end…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.