What effect does histone acetylation have on Gene 1?

Q: What is the substrate of a histone acetyltransferase?

A: Substrate are molecule on which an enzyme acts.  Transcription is the process by which information…

Q: Can nonsense mutations be reversed by hydroxylamine? Why or why not?

A: Mutations are the events that results in change in the DNA sequence. Mutations can be a result of…

Q: How does histone variation regulate gene expression in eukaryotic cells?

A: In the nucleus DNA is coiled and packed in the form of chromosomes. DNA wounds on histone and forms…

Q: A gene contains 30% thymine. What is the percentage of pyrimidines present in this segment? Explain.

A: Purines and pyrimidines are chemical molecules that play a role in the production of DNA and RNA and…

Q: What chemical and structural properties of histones enable them to successfully package eukaryotic…

A: Histones are basic proteins found in eukaryotic cells that associate with DNA by packaging the DNA…

Q: What is a histone variant?

A: Proteins are large biomolecules consisting of one or more long chains of amino acids residues.…

Q: What are the roles of proteins in histone modification?

A: Within a eukaryotic cell, DNA is packaged and organized into long specific structures called…

Q: What is the difference between chromatin-remodeling and histone modification?

A: In any event nine unique sorts of histone changes have been found. Acetylation, methylation,…

Q: what is the highly compacted strongly staining region of the chromosome with no transcriptional…

A: The highly compacted strongly region of the chromosome with no transcriptional activity is…

Q: Which type/s of histones is/are not part of the histone octamer wrapped by DNA strands but is found…

A: Histones proteins are present as octamer (eight) complex at the center of nucleosome. It consist of…

Q: What are the roles of the core histone proteins and of histone H1 inthe compaction of eukaryotic…

A: The basic protein that serves the function of DNA packaging in order to form nucleosome in the…

Q: Why transposons are called jumping genes?

A: A sequence of DNA sequence that has the ability to move or insert itself at a new location in the…

Q: What is the Evidence for a triplet code?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: How histone deacetylases (HDACs) remove acetyl groups from histone tails ?

A: Histones are highly basic proteins that play an essential role in the packaging chromosomes.…

Q: Why are histone modifying enzymes important?

A: Chromosomes are thread-like structures that are present in the nucleus of the cell. The basic unit…

Q: What are the roles of the core histone proteins versus the role of histone H1 in the compaction of…

A: The eukaryotic cells contain different organelles like lysosomes, mitochondria, Golgi apparatus,…

Q: What are histone acetyl transferases (HATs)?

A: Histones are proteins that are associated with DNA inside the nucleus of eukaryotic organisms. The…

Q: What is the major form of DNA methylation that is seen in eukaryotes? At what type of DNA sequence…

A: Step 1 Deoxyribonucleic acid (DNA) methylation is am epigenetic procedure that takes place by adding…

Q: Since eukaryotic chromosomes are assembled with histone proteins, how are replication and…

A: Histone  These are the proteins that are basic in nature as they are abundant in the amino acids…

Q: Is heterochromatin transcriptionally active?

A: Deoxyribonucleic acid (DNA) is the genetic material made up of nitrogenous bases, pentose sugars,…

Q: How does adding a methyl or acetyl group to a histone protein alter gene activity?

A: Histones are proteins, found in eukaryotic nuclei that order DNA into a shape. The histone molecules…

Q: What are the two types of transposable elements?

A: Transposable elements are known as stretches of DNA molecules and they can move from one place to…

Q: which exons become spliced together?

A: Splicing is the editing of the nascent precursor messenger ribonucleic acid (RNA) called pre-mRNA…

Q: How Histone acetylation is catalyzed ?

A: Histones are basic proteins. These proteins are associated with the DNA. DNA association with…

Q: Why does histone deacetylase action tend to repress transcription?

A: Transcription is the process of producing messenger RNA. This mRNA synthesizes proteins which is…

Q: What mutagen results to the formation of thymine dimers?

A: Asked : Mutagen which results to the formation of thymine dimers

Q: Why eukaryotic genes are called split genes?   What is alternative RNA splicing?

A: Gene is the biological and functional unit of cells. They consists of DNA that is present on the…

Q: What are conditions for Histone modification ?

A: The length of the DNA is way too high to accommodate in the nucleus. Therefore the DNA is packed to…

Q: What enzymes are involved in histone acetylation anddeacetylation?

A: Histone acetylation and deacetylation are critical processes in the regulation of the expression of…

Q: What are the major types of covalent modification of histones?

A: The major types of covalent modifications of histone proteins are as follows:

Q: What are the roles of histone deacetylation and histoneacetylation in gene regulation, respectively

A: A gene is the essential physical and functional unit of heredity. They are comprised of DNA…

Q: How are mutations in histone acetylation (HAT) genes linked to cancer?

A: HATs or histone acetyltransferase are enzymes that acetylate the lysine amino acid on histone…

Q: What are some of the processes that affect gene regulation by altering chromatin structure?

A: The mechanism of encoding of proteins by a gene which regulates cellular functions is known as gene…

Q: Are anticodons only AAG? or, do they have different sequences?

A: Anticodons are present on transfer RNA or tRNA.The tRNAs are attached with specific amino acids and…

Q: What are HU and H-NS (Histone-like Nucleoid Structuring) proteins ?

A: Chromatin is a substance found within chromosomes that is made up of DNA and protein. The DNA…

Q: What is the effect of acetylation of a lysine residue on the charge of a histone protein? Of lysine…

A: DNA methylation and lysine modifications comprise major epigenetic processes on chromatin, which…

Q: How did telomerase respond to acute stress?

A: By lengthening telomeres and supporting cell growth and longevity, telomerase activity is critical…

Q: Do eukaryotes have transposable elements?

A: Transposable elements or TEs are also referred to as jumping genes. They are the DNA sequence that…

Q: How do histones differ from the DNA-binding proteins described in the preceding section?

A: The genome contains DNA which is packaged into chromosomes in the nucleus of the cell with the help…

Q: What are the histone types found in the octamer wrapped by DNA strands?

A: Introduction: The DNA is wrapped around the histone protein, and the structure formed is called a…

Q: What are the consequences of histone acetylation?

A: Histones are highly basic proteins with a lot of lysine and arginine residues that are present in…

Q: What effect do you predict this histone variant would have when it is inserted into chromatin?

A: Answer: Histones are the octamer protein which has been wrapped by the DNA forming strong…

Q: You are studying a small eukaryotic gene of about 2000 bp in length. About how many copies of…

A: There are histone octamers found in the genetic arrangement whose knowledge can be used to answer…

Q: What is the purpose of histone tail modification?

A: Histones are a family of basic proteins, which associate with deoxyribonucleic acid (DNA) in the…

Q: Why is transcriptionally active chromatin ∼10 times more susceptible to cleavage by DNase I than…

A: Chromatin : It is the material that makes up a chromosome that consists of DNA and proteins. The…

Q: What changes take place in chromatin structure, and what role do these changes play in eukaryotic…

A: Step 1 DNA (deoxyribonucleic acid) coil many times to fit into the cell’s nucleus. The DNA to attain…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.