Which of the following statements is NOT true about chromatin architecture? A. The histone tails on heterochromatin are deacetylated B. Heterochromatin is heavily methylated C. Euchromatin is more likely to contain genes that are expressed at that time D. Euchromatin is heavily methylated

Which of the following statements is NOT true about chromatin architecture? A. The histone tails on heterochromatin are deacetylated B. Heterochromatin is heavily methylated C. Euchromatin is more likely to contain genes that are expressed at that time D. Euchromatin is heavily methylated

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter29: Transcription And The Regulation Of Gene Expression

Section: Chapter Questions

Problem 20P: Chromatin decompaction is a preliminary step in gene expression (Figure 29.48). How is chromatin...

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Question

Which of the following statements is NOT true about chromatin architecture?

A. The histone tails on heterochromatin are deacetylated

B. Heterochromatin is heavily methylated

C. Euchromatin is more likely to contain genes that are expressed at that time

D. Euchromatin is heavily methylated

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Step 1: Explaining chromatin and its types

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Step 2: comparing euchromatin and heterochromatin

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Step 3: Explaining histone

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Heterochromatin consists of a) region of euchromatin devoid of histones. b) an AT-rich region occurs every 200 base pairs. c) decondensed, transcriptionally active chromatin. d) highly condensed, transcriptionally inactive chromatin
Which of the following is associated with active chromatin? Check all that apply. A. Centromeres B. heterochromatin C. histone acetylation D. Polytene puffs E. metaphase chromasomes F. transcription of machinery
A chromatin-remodeling complex may a. change the locations of nucleosomes. b. evict nucleosomes from DNA. c. replace standard histones with histone variants. d. do all of the above.
Loosening the chromatin structure occurs because of Select one: a. Lysine methylation b. Lysine acetylation c. Lysine phosphorylation d. Lysine sumoylation
_____ is the combination of a seat, elation, another modifications to the histones that allow for changes in DNA winding and unwinding a. Epigentics b. Histone code c. Heterochromatin d. Post translational modifications
The conversion of euchromatin into heterochromatin involvesa. the formation of more nucleosomes.b. the formation of less nucleosomes.c. a greater compaction of loop domains.d. a lesser compaction of loop domains.e. both a and c.
How many copies of the H2B histone would be found in chromatin containing 50 nucleosomes? a. 5 b. 10 c. 50 d. 100
Histones form more accessible chromatin because of Select one: a. Reduced electrostatic attraction between the histone and the negatively charged DNA backbone b. Increased electrostatic attraction between the histone and the negatively charged DNA backbone c. Reduced covalent bonding between the histone and the negatively charged DNA backbone d. Increased covalent bonding between the histone and the negatively charged DNA backbone
Changes in chromatin packing correlate with changes in gene expression in most cells. Why do you think this is the case?
Which one of the following statements about nucleosomes is false? a) The DNA double helix wraps around the nucleosome. b) The sequence of amino acid in a histone tail is altered during chromatin remodeling. c) A nucleosome is composed of 8 histone proteins; two copies of each type of histone. d) A large percent of the nucleosome is positively charged.
Which of these is NOT true of nucleosomes? A. Some post-translational modifications to histone proteins serve as binding sites for transcription factors. B. The position of nucleosomes is fixed on the genome and can not be changed. C. The position and post-translational modifications of histones can be inherited through mitosis. D. The binding between DNA and histone proteins can be disrupted by post-translational modifications.
The picture below depicts electron micrographs of the major levels of chromatin structure. Match each of the listed conditions with the most likely levels of chromatin structure under that condition.