What is a key characteristics of a G protein-linked receptors? a. it allows ions to flow through b. it changes confirmation and becomes autophosporylated c. it is a serpentine transmembrane receptor?
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What is a key characteristics of a G protein-linked receptors?
a. it allows ions to flow through
b. it changes confirmation and becomes autophosporylated
c. it is a serpentine transmembrane receptor?
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- Do you consider GPCR is intracellular or membrane bound receptor?? Explain itCompare and contrast GPCR and RTK receptors with respect to (a)structure (especially the transmembrane region), (b) activation mechanism, and (c) initial signal transduction across the membrane.. which of the following statements about heterotrimetric G proteins and their receptors is incorrect? A: when GTP binds to the alpha subunit of the G protein, the beta-gamma subunit dissociates from the alpha subunit B: G-protein coupled receptors contain nine transmembrane alpha helices C: binding of arrestin causes removal of the receptor from the membrane D: G protein- coupled receptors may be desensitized by serine phosphorylation I had chosen option A and got it wrong. What is the Correct answer and explain how it is. Also, where did i go wrong in choosing option A?
- Explain why a peptide (protein) ligand can’t use a receptor inside the cell while an asteroid has no problem using an intracellular receptor.Estimate the binding affi nity of a ligand for its receptor from the followingdata:Molecule X is a soluble protein that is secreted in response to extracellular signal Y. Which sorting signal must molecule X have?
- A) Please explain what a G protein coupled receptor is. Please explain how G protein interacts with this receptor. B) Please explain the kind of reactions that follow binding a specific ligand to a G protein coupled receptor. What do these reactions do in the cell? C) How do these reactions work in the cell. What is the function of these reactions in the cell? How do the reactions proceed?What type of molecules serve as ligands for intracellular vs. membrane receptors?Phospholipase C cleaved the membrane lipid PIP2 into IP3 and DAG in response to which type of membrane receptor being activated?
- The receptor-associated proteins called G proteins... A. bind GTP. B. can activate or inhibit an effector protein, e.g. adenyl cyclase. C. interact with membrane-associated proteins to influence their function. D. both a and b E. a, b, and cIntracellular receptors bind to signaling molecules that are A. anionic. B. cationic. C. nonpolar. D. polypeptides.what are the function for 1.G protein-coupled receptor 2.G protein