What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter20: Iv Medication And Titration Calculations
Section: Chapter Questions
Problem 24SST
icon
Related questions
Question

What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?

Based on the table below, what would be the recommended dosage of "Levofloxacin 500 mg IV every 24 hours" if the 72-year-old patient weight is 78 kg and has a serum creatinine: 3.2 mg/dL?

 

 

Dose regimen
250 mg/24 h
500 mg/24 h
500 mg/12 h
Creatinine clearance
first dose: 250 mg
first dose: 500 mg
first dose: 500 mg
50 - 20 ml/min
then: 125 mg/24 h
then: 250 mg/24 h
then: 250 mg/12 h
19-10 ml/min
then: 125 mg/48 h
then: 125 mg/24 h
then: 125 mg/12 h
< 10 ml/min (including
haemodialysis and CAPD)
then: 125 mg/48 h
then: 125 mg/24 h
then: 125 mg/24 h
1
1No additional doses are required after haemodialysis or continuous ambulatory peritoneal dialysis (CAPD).
Transcribed Image Text:Dose regimen 250 mg/24 h 500 mg/24 h 500 mg/12 h Creatinine clearance first dose: 250 mg first dose: 500 mg first dose: 500 mg 50 - 20 ml/min then: 125 mg/24 h then: 250 mg/24 h then: 250 mg/12 h 19-10 ml/min then: 125 mg/48 h then: 125 mg/24 h then: 125 mg/12 h < 10 ml/min (including haemodialysis and CAPD) then: 125 mg/48 h then: 125 mg/24 h then: 125 mg/24 h 1 1No additional doses are required after haemodialysis or continuous ambulatory peritoneal dialysis (CAPD).
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Similar questions
Recommended textbooks for you
Curren'S Math For Meds: Dosages & Sol
Curren'S Math For Meds: Dosages & Sol
Nursing
ISBN:
9781305143531
Author:
CURREN
Publisher:
Cengage
Essentials of Pharmacology for Health Professions
Essentials of Pharmacology for Health Professions
Nursing
ISBN:
9781305441620
Author:
WOODROW
Publisher:
Cengage