What is the most appropriate probability distribution to use? What is the probability that 60 mRNA transcripts are made until the 4th burst? Suppose another researcher is only interested in the number of mRNA until the first "burst". What is the probability that 18 mRNA transcripts are made until the 1st burst?

What is the most appropriate probability distribution to use? What is the probability that 60 mRNA transcripts are made until the 4th burst? Suppose another researcher is only interested in the number of mRNA until the first "burst". What is the probability that 18 mRNA transcripts are made until the 1st burst?

College Algebra

10th Edition

ISBN:9781337282291

Author:Ron Larson

Publisher:Ron Larson

Chapter8: Sequences, Series,and Probability

Section8.7: Probability

Problem 11ECP: A manufacturer has determined that a machine averages one faulty unit for every 500 it produces....

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Question

Transcriptional bursting is a fundamental property of genes in which transcription from DNA to mRNA can occur in "bursts" or "pulses". Consider the experiment of observing the number of mRNA transcriptions until observing four "bursts". Suppose the probability of a burst in gene expression is 6.5%.

What is the most appropriate probability distribution to use?

What is the probability that 60 mRNA transcripts are made until the 4th burst?

Suppose another researcher is only interested in the number of mRNA until the first "burst". What is the probability that 18 mRNA transcripts are made until the 1st burst?

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