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- 1. Why is the use of monosodium glutamate (MSG) highly debated?14) Should you measure the radius or diameter of the zone of inhibition?Which of the following statements about inhibition is true? a. Allosteric inhibitors and allosteric activators are competitive for a given enzyme. b. If an inhibitor binds the active site, it is considered noncompetitive. c. If an inhibitor binds to a site other than the active site, this competitive inhibition. d. A noncompetitive inhibitor is believed to change the shape of the enzyme, making its active site inoperable. e. Competitive inhibition is usually not reversible.
- To measure the zone of inhibition you should measure the circumstances of the each circle?1. Explain chemotherapy in terms of specific inhibition 2. Explain why enzyme activity declines at (a)high temperature and (b) presence of heavy metal ions.What is a zone of inhibition?How did you measure the zone of inhibition?Which unit of measurement was used?
- How can we distinguish between pure and mixed noncompetitive inhibition?5.Aspirin isthedrug,used for the decreasing ofinflammatory reaction and temperature. 1)Describe the mechanism of aspirin action. 2) What types of reversible inhibition do you know.3)Give the examples of drugs acting as such inhibitors.Identify the type of inhibition (competitive, noncompetitive, uncompetitive)
- Why does a pure noncompetitive inhibitor not changethe observed KM?1D. What kind of inhibitor is GMP-PCP?Inhibitor X exerts which of the following effects on the above enzyme (lactase)? (inhibitor X changes lactase activity to a Vo of 0.10 mM per minute when [S] = 1.0 mM, and a Vo of 0.133333333333 mM per minute when [S] = 2.0 mM) pure non-competitive inhibition uncompetitive inhibition competitive inhibition all of the above none of the above