What kind of changes happens in the structure of proteins when they are separately incubated with concentrated salt solutions and organic solvents?

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 6.4P
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What kind of changes happens in the structure of proteins when they are separately incubated with concentrated salt solutions and organic solvents?

pk,
pK1
(—соон)
pk2
(–NH )
pKr
R Grubu
Proteinlerde
Bulunma Yüzdesi
pl
Gly G
75
2.34
9.60
5.97
7.2
Ala A
89
2.34
9.69
6.01
7.8
Pro P
115
1.99
10.96
6.48
5.2
Val V
117
2.32
9.62
5.97
6.6
Leu L
131
2.36
9.60
5.98
9.1
lle I
131
2.36
9.68
6.02
5.3
Met M
149
2.28
9.21
5.74
2.3
Phe F
165
1.83
9.13
5.48
3.9
181
9.11
Tyr Y
Trp W
2.20
10.07
5.66
3.2
204
2.38
9.39
5.89
1.4
Ser S
105
2.21
9.15
5.68
6.8
Thr T
119
2.11
9.62
5.87
5.9
Cys C
121
1.96
10.28
8.18
5.07
1.9
Asn N
132
2.02
8.80
5.41
4.3
Gln Q
146
2.17
9.13
5.65
4.2
Lys K
His H
146
2.18
8.95
10.53
9.74
5.9
155
1.82
9.17
6.00
7.59
2.3
Arg R
174
2.17
9.04
12.48
10.76
5.1
Asp D
133
1.88
9.60
3.65
2.77
5.3
Glu E
147
2.19
9.67
4.25
3.22
6.3
Transcribed Image Text:pk, pK1 (—соон) pk2 (–NH ) pKr R Grubu Proteinlerde Bulunma Yüzdesi pl Gly G 75 2.34 9.60 5.97 7.2 Ala A 89 2.34 9.69 6.01 7.8 Pro P 115 1.99 10.96 6.48 5.2 Val V 117 2.32 9.62 5.97 6.6 Leu L 131 2.36 9.60 5.98 9.1 lle I 131 2.36 9.68 6.02 5.3 Met M 149 2.28 9.21 5.74 2.3 Phe F 165 1.83 9.13 5.48 3.9 181 9.11 Tyr Y Trp W 2.20 10.07 5.66 3.2 204 2.38 9.39 5.89 1.4 Ser S 105 2.21 9.15 5.68 6.8 Thr T 119 2.11 9.62 5.87 5.9 Cys C 121 1.96 10.28 8.18 5.07 1.9 Asn N 132 2.02 8.80 5.41 4.3 Gln Q 146 2.17 9.13 5.65 4.2 Lys K His H 146 2.18 8.95 10.53 9.74 5.9 155 1.82 9.17 6.00 7.59 2.3 Arg R 174 2.17 9.04 12.48 10.76 5.1 Asp D 133 1.88 9.60 3.65 2.77 5.3 Glu E 147 2.19 9.67 4.25 3.22 6.3
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