What volume (mL) of the prepared high alcoholic elixir is needed if the prescription requires 100 mL of an alcoholic elixir with 65% v/v alcoholic strength? Low alcoholic elixir alcoholic strength: 25% High alcoholic elixir alcoholic strength: 75% 40.00 mL 10.00 mL 80.00 mL 20.00 mL
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- TRUE OR FALSE 1. Medicated elixirs are advantageous in adjusting the dose that may be increased or decreased by simply taking more or less of the elixir. 2. It is impossible to increase or decrease the amount taken of one ingredient without and automatic and corresponding adjustment in the dose taken of the other. 3. Then the alcoholic solution is added to the aqueous solution in order to maintain the highest possible alcoholic strength. 4. Saccharin is used for elixirs with low alcoholic content required only in small amounts. 5. Proportion of alcohol varies widely in elixirs since the individual components. 6. The final mixture of elixir will be clear since the separation of some of the flavoring oils by the reduced alcoholic concentration. 7. Permission of the oil globules oil to coalesce leads to difficulty in filtration. 8. Wetting the filter paper and collection flask using the solvent ensures continued solubility of the alcoholic ingredients. 9. Elixirs are best stored in…b) % yield of ethanol from molasses (we used 50 mL of the molasses solvent for both distillation) c) % yield ethanol from sugars, assuming approximately half of molasses is reactive sugars C12H22O11 (sucrose) -> 4 CH3CH2OH + 4 CO2 my Simple distillation % ethanol was 100% (0.774) and my fractional distillation % ethanol was 100% (0.774).When 10.6 gram of a nonvolatile substance is dissolved in 740 gram of ether, it’s boiling point is raised 0.284 0 What is the molecular weight of the substance? (kb ether = 2.11 0C.kg/mol)
- 14. A pharmacist mixes 100 mL of syrup containing 85 % (w/v) sucrose with 20 mL of vancomycin 50 mg/mL sucrose-free solution. What is the final concentration of sucrose (w/v)?Indicate the appropriate protocol below to prepare the required solution. a) Solution 5 Preparation: Prepare: 10 mL of 23% mannitol From: solid mannitol Procedure: b) Solution 2 Preparation: Prepare: 0.5 liters of 0.01 mg/mL ascorbic acid From: solid ascorbic acid , MW = 176.1 g/mol Procedure: C) Solution 3 Preparation: Prepare: 1 liter of 150 mM Tris From: 1 Molar Tris stock solution Procedure:What is the concentration in units of grams of dye per liter of solution ,of the dilute dye solution that is produced as follows? transfer 19.53 ml of stick solution (6.10g/L) to a 200.0Ml volumetric flask and dilute to the 200 ml line with deionized water. Correct number of significant figs
- An extra strength Tylenol caplet contains 500 mg of acetaminophen (C8H9NO2) as one of its active ingredients. a. How many Tylenol caplets will contain 0.050 mol of acetaminophen? _________ caplets b. How many acetaminophen molecules do three caplets contain? __________________ molecules6 I- + BrO3- + 6 H+ ----- 3 I2 + Br- + 3 H2O Rate= k[I-]m[BrO3-]n[H+]p rate= (∆[I2])/(3*∆time) [I-] 0.010M [S2O3-2] 0.0010M H2O [BrO3-] 0.04M HCl 0.10M Starch Indicator (sec.) Volume, ml Volume, ml Volume, ml Volume, ml Volume, ml 1 10 10 20 10 10 1-3 drops 301.90 2 20 10 10 10 10 1-3 drops 213.28 3 10 10 10 20 10 1-3 drops 214.92 4 10 10 10 10 20 1-3 drops 86.45 Temperature of Reaction: _______20 C________ 1. Using the dilution equation (M1V1 = M2V2) calculate the concentration of the I-, BrO3- and the H+ (HCl) in the final mixture just prior to any reaction. 2. Calculate the rate for each experiment as explained in the background information. 3. Using the information above determine the rate law (m, n and p) for the reaction. Show all calculations/reasoning in your notebook. m_____________ n_________________ p…SOLUBLE if the first substance is soluble in the second substance and INSOLUBLE if it does not dissolve. 1. Hexane + water SOLUBLE INSOLUBLE 2. Cyclohexene + water SOLUBLE INSOLUBLE 3.Vanillin + sodium hydroxide * SOLUBLE INSOLUBLE 4.Cinnamaldehyde + ethyl alcohol SOLUBLE INSOLUBLE 5.Chloroform + sodium hydroxide * SOLUBLE INSOLUBLE 6.Iodoform + ethyl alcohol * SOLUBLE INSOLUBLE 7.Glycerol + water * SOLUBLE INSOLUBLE
- 1.1 Calculate the amount of NaCl needed to make the prescription isotonic. Rx Ephedrine sulfate (E = 0.23) 1 g Sodium chloride qs Sterile water, ad 50 mL Sig. make isotonic solution 1.2 If one desired to use dextrose (E=0.16) instead of NaCl to adjust the tonicity, how much dextrose would be required? 2. Make the following solution isotonic with respect to membrane. Provided that you have isotonic diluting solution, calculate the volume in mL of isotonic solution that may be prepared by mixing drug with water. Rx Phenacaine (E = 0.20) 0.06 g Sterile water, ad 100 mL Sig. make isotonic solution INSTRUCTIONS: Justify your answer through calculations which contains; GIVEN FORMULA USED SUBSTITUTION CALCULATED VALUE FINAL ANSWERA sunscreen contains 6% oxybenzone and 3% avobenzone bymass. If a bottle contains 40. g of sunscreen, how many kilogramsof oxybenzone and avobenzone are needed to manufacture1 ton of sunscreen? How many bottles of sunscreen can beproduced for 1 ton of sunscreen?How many milliliters of a thimerosal 25% stock solution must be used to prepare 100 ml of thimerosal topical solution of 1:1000 ratio strength? A diphenhydramine elixir contains 12.5 mg drug in one teaspoon. The volume of oral vehicle that is to be added to 100 ml of this elixir to reduce its strength by one half its original strength is: When preparing an ounce of 1% hydrocortisone cream the technician made an error and added 200 mg of hydrocortisone in the preparation. Calculate the additional amount of hydrocortisone powder that should be added to the 1 ounce cream to make the strength 1%. Onabotulinumtoxin A (BOTOX) is available in a 100 units vial for reconstitution. 2.5 ml of sterile preservative free normal saline was added to this vial and reconstituted. How many units of botox is present in 0.1 ml of the dilution? (ignore any volume changes during reconstitution)