Which of the following is false about cyclin-cdk complexes? Cdk's do not have to bind to cyclin proteins for complex to be active. OCdk/cyclin complexes phosphorylates proteins required to trigger next cell cycle phase. Process acts as molecular brakes to ensure cell is ready to continue with cell cycle. OCyclin concentrations increase gradually, but cdk must be phosphorylated by specific kinase for complex to be active |0|0

Which of the following is false about cyclin-cdk complexes? Cdk's do not have to bind to cyclin proteins for complex to be active. OCdk/cyclin complexes phosphorylates proteins required to trigger next cell cycle phase. Process acts as molecular brakes to ensure cell is ready to continue with cell cycle. OCyclin concentrations increase gradually, but cdk must be phosphorylated by specific kinase for complex to be active |0|0

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter10: Cell Reproduction

Section: Chapter Questions

Problem 8RQ: S. Chromosomes are duplicated during what stage of the cell cycle? G1 phase S phase prophase...

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Which of the following is true with respect to cyclins and CDKs? A) CDKs promote progression of the cell cycle, cyclins function to inhibit progression of the cell cycle B) CDKs are the checkpoints in the cell cycle, and when bound to cyclins, they stop progression of the cell cycle C) CDKs will only work to promote progression of the cell cycle when complexed with their designated cyclins D) CDKs are rarely expressed during a cell's cycle, unless cyclins are present to act as transcription factors .
Which of the following is the primary method by which cyclin proteins are regulated to influence entry into the cell cycle or transition from one stage to the next? A. Transcriptional upregulation and translation followed by targeted ubiquitin-mediated degradation by a proteasome. B. Phosphorylation to regulate the activity of the kinase site. C. An activating phosphorylation and an inactivating phosphorylation. D. All of these are mechanisms that can be used to regulate cyclins.
Q. Cyclins and CDK(inase) complexes regulate the cell cycle. Which of the following statements is true? A. Cyclins activate CDKs which remove phosphates from other proteins. B. Cyclins activate CDKs which add phosphates to other proteins. C. CDKs activate cyclins which remove phosphates from other proteins. D. CDKs activate cyclins which add phosphates to other proteins.
Which of the following statements about the cell cycle is TRUE? a. The protein APC blocks cells from entering anaphase b. CDKs are degraded after each cell cycle phase by the addition of a ubiquitin chain to the proteins c. A kinase is a protein that adds a ubiquitin chain to other proteins Cyclin activity is necessary, but not always sufficient, for CDK activation d. Cyclin proteins must be degraded before Cdk proteins can be activated
Which of the following is NOT a checkpoint that controls the progression of cell cycle? The metaphase checkpoint determines if all chromosomes are attached to the spindle apparatus Cytokinesis involves the formation of cleavage furrow to separate the cells The G2 checkpoint checks for DNA damage and determines if all of the DNA is replicated Cyclins and cyclin dependent kinases are protejns that are responsible for advancing a cell through the phases of the cell cycle
Which of the following would lead to increased progression through the G1/S cell cycle check point? CDK is produced at lower than normal levels. E2F is produced at lower than normal levels. Cyclin D and E are produced at lower than normal levels. Retinoblastoma protein was never phosphorylated. Retinoblastoma protein is produced at lower than normal levels.
Maturation promoting factor, MPF, is a cyclin-CDK complex that catalyzes the phosphorylation of other proteins to start mitosis. The activity level of MPF is dependent on the relative concentrations of the cyclin and CDK components of MPF (Figure 1). Based on Figure 1, which of the following describes the role of cyclin in the regulation of the cell cycle? a.During S phase, the cyclin level remains the same because DNA replication is occurring. b.During G2 phase, the cyclin level remains low, causing MPF activity to decrease, which leads cells to initiate mitosis. c.During G1 phase, the cyclin level decreases to signal the start of the resting phase of the cell cycle. d.During M phase, the cyclin level peaks, resulting in an increased binding frequency with CDK.
Which of the following statements regarding cyclin B is FALSE? Group of answer choices It is a component of the mitosis or maturation promoting factor (MPF) Its production and activation is linked to extracellular stimuli It interacts and activates CDK1 protein kinase Its destruction by APC/C signals the end of mitosis All of the above are true
Which of the following would be expressed at varying levels during different parts of the cell cycle? A. cyclin-dependent kinases B. RNA polymerase C. cyclins D. Glycolysis enzymes
Which structure will form during the cytokinesis of a plant cell? septum cell plate cleavage furrow Which choice is an example of a product that is not a negative regulator protein. p21 RB1 p53 Cdk Which cell cycle checkpoint occurs during the mitotic phase of the cell cycle? M G2 G1 The mitotic phase of the cell cycle consists of cell growth DNA replication mitosis and cytokinesis The formation of a cleavage furrow only occurs during the cytokinesis of bacterial cells plant cells animal cells Single-celled eukaryotic organisms reproduce by the cell division process called reduction division mitosis meiosis binary fission In which stage of the cell cycle do cells that are not going to divide further are shunted into: S G1 G0 G2 Human sperm or egg cells contain one set of chromosomes which is a configuration known as __________ or ________. diploid, 2n diploid, n haploid, 2n haploid, n…
Which of the following need to be expressed to get past the G1 checkpoint and why? Select one: a. All the answers are correct and needed to progress the cell past the G1 checkpoint by expressing the enzymes necessary for DNA replication. Once these proteins are all expressed, the cell has moved past G1 into S phase. b. Primase because this enzyme is needed for DNA replication moving the cell from G1 to S. c. Cyclins because the accumulation of specific cyclins will turn on CDKs needed to turn on gene expression for proteins involved in DNA replication, moving the cell from G1 to S. d. DNA helicase because this protein is needed for DNA replication (part of S phase). So expression will help progress the cell from G1 to S.
Choose all of the TRUE statements. Hint: 4 statements are true. Cytokinesis occurs the same way in both plant and animal cells. Sister chromatids are genetically identical. The term chromosome can be used to describe both chromosomes composed of one and two chromatids. Mitosis results in daughter cells that are genetically identical to the parent cell. All eukaryotic somatic cells are diploid. Cyclin dependent kinases are present but not active in cell cycle regulation without the presence of cyclin proteins. Chromosomes are always visible in the cell.