Answered: Which of the following is the most…

Which of the following is the most active acyl compound in terms of susceptibility to react? A. ethylacetate B. acetamide C. acetic anhydride D. acetyl chloride E. acetic acid

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter19: Enolate Anions And Enamines

Section: Chapter Questions

Problem 19.32P

See similar textbooks

Related questions

Q: Draw a stepwise mechanism for the conversion of geranyl diphosphate to α-terpinene. Steroids

A: In this question, we will Draw a complete stepwise mechanism for this given transformation. You can…

Q: What product result from nitration of benzonitrile ?

A: Reaction in which there in introduction of nitro group is called as nitration reaction. It is…

Q: Draw a stepwise mechanism for the conversion of geranyl diphosphate to a-terpinene. OPP a-terpinene

A: The given reactant is geranyl diphosphate and the product is α-terpinene. The mechanism for the…

Q: Draw the curly arrow reaction mechanism to show bonds being broken/formed. What is the function of…

A: The functional groups are key constituents of a molecule that provides a notable reaction to the…

Q: Consider the following compounds: Compound E: benzoic acid Compound F: benzoyl chloride Compound G:…

A: Oxidation is a process by which a carbon atom gains bonds to more electronegative elements like…

Q: Synthesis of sulfanilamide

A: The synthesis of sulfanilamide has to be given.

Q: Nabumetone is a pain reliever and anti-inammatory agent sold under the brand name of Relafen.a.…

A: a.

Q: Is the acid-catalyzed hydrolysis of acetamide a reversible or an irreversible reaction? Explain.

A: The acid-catalyzed hydrolysis of acetamide is an irreversible reaction. This is because the last…

Q: Write equations for the following : a. Aldehydes+ Acidified Potassium Permanganate b. Aldehydes+…

A: We have to write equations for the following : a. Aldehydes+ Acidified Potassium Permanganate b.…

Q: What cyanohydrin and carbonyl compound are formed when amygdalin is metabolized in a similar manner…

A: The derivative compound of cyanohydrin is amygdalin. The metabolism of amygdalin involves 2 steps.…

Q: What is the name of the macrolide shown? A. Erythromycin A B. Erythromycin B C. Erythromycin C D.…

Q: Which of the following method is the best method for the synthesis of propanoic acid A.)…

Q: Quebrachamine is isolated from quebracho bark and it has adrenergic blocking activities for a…

Q: Explain the following observation. Pyridine is a less weak base than pyrol.

A: Pyrol is a heterocyclic compound with the nitrogen atom incorporated within a five-membered ring…

Q: Draw the structure corresponding to each name.a. 5-methylheptanoyl chloride b. isopropyl…

A: The structures of the given compounds are :

Q: MCQ 25: The reaction involving the breakdown of the water molecule is known as A. heterolytic B.…

Q: Explain the Steps in the Acetoacetic Ester Synthesis ?

A: The acetoacetic ester synthesis guides the conversion of ethyl acetoacetate to a methyl ketone. This…

Q: Each molecule of fatty acid ester provides how many equivalents of carboxylate acid salts?

Q: Draw the structure for each of the following: a. phenyl acetate d. N-benzylethanamide e.…

Q: By chlorination of benzoic acid major product is Select one: a. 3-clorobenzoic acid b.…

A: We have to tell the major product of chlorination of benzoic acid

Q: Aspirin is an anti-inflammatory agent because it inhibits the conversion of arachidonic acid to…

A: Since the ester group will take the acidic H present in OH of the enzyme and form a carbocation on…

Q: N-Methylbenzamide tert-Butyl butanoate p-Methylbenzoic anhydride

A: Given,

Q: Which of the following is the most active acyl compound in terms of susceptibility to react? A.…

A: The question is based on the concept of organic reactions. We have to identify which of the given…

Q: Draw a stepwise mechanism for the conversion of geranyl diphosphate to α-terpinene.

A: In the first step, the removal of OPP group from geranyl diphosphate which results in the formation…

Q: What Grignard reagent and carbonyl compound can be used to prepare the antidepressant venlafaxine…

A: The crabonyl compound and the grignard reagent that can be used to form venlafaxine is as follows:…

Q: Explain with reason why ester cannot be converted into acylchloride?

A: We cannot convert ester into acyl chloride, Because reaction is going from less reactive to more…

Q: a. Is (R)-lactic acid dextrorotatory or levorotatory? b. Is (R)-sodium lactate dextrorotatory or…

A: When a carbon atom is attached to four different substituents, then the carbon is called asymmetric…

Q: 12. You can distinguish epinephrine hydrotartrate from norepinephrine hydrotartrate by? A. Water…

A: The adrenal medulla produces epinephrine hydrotartrate, also known as adrenaline, and norepinephrine…

Q: Write an equation for the aldol condensation of two molecules of propanal.

A: For aldol condensation reaction alpha hydrogen are required and strong base is used

Q: Write chemical reaction of butanal added with ethanol. B. Write an equation for the aldol…

Q: Draw and explain the mechanism for the ammoxidation of propene which leads to the formation of…

Q: Aspirin is an anti-inammatory agent because it inhibits the conversion of arachidonic acid to…

Q: Ketoprofen and ibuprofen both have a propanoic acid substituent. Explain why the identical subunits…

Q: Draw the component of the opioid analgesic structure which is consistent between morphine,…

Q: What is the Methods used to Synthesis of IMINES.

Q: What is the product when a dissulfide is reduced? A) an aldehyde. B) a ketone. C) sulfuric acid. D)…

A: Given: Reduction of disulfide To find : Product formed Solution: Reduction is the process in which…

Q: ● Why is the reaction with acetaminophen regiospecific?

A: As multiple questions are given, I am allowed to answer one question at a time. Please re upload the…

Q: Draw the structure corresponding to each common name: a. α-methoxyvaleric acid b. β-phenylpropionic…

A: a) Since in the name we have methoxy group at position α. Hence there will be a methoxy group…

Q: Explain nucleophilic addition to the aldehyde to form analcohol ?

A: Given: Explain nucleophilic addition to the aldehyde to form an alcohol.

Q: Evaluate blooms taxonomy for the question given: An unknown aldehyde (X) on reacting with an…

A: Oxidation reaction is the reaction in which addition of oxygen take place to the given species.…

Q: cyanohydrin from a ketone

Q: Draw two derivatives of penicillamine, one with a bioisosteric replacement for the carboxylic acid…

Q: What Grignard reagent and carbonyl compound can be used to prepare theantidepressant venlafaxine…

A: Alcohols can be prepared from the reaction between carbonyl group and a Grignard reagent.

Q: When an ester is treated with a Grignard reagent, What situation arises ?

A: What situation arises, when an ester is treated with grignard reagent has to be given.

Q: Nabumetone is a pain reliever and anti-inflammatory agent sold under the brand name of Relafen. a.…

A: a) Please find below a synthesis of nabumetone from ethyl acetoacetate.

Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

Which of the following is the most active acyl compound in terms of susceptibility to react?

A. ethylacetate
B. acetamide
C. acetic anhydride
D. acetyl chloride
E. acetic acid

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

What the difference between Hapticity and Homoletic carbonyls
What product is formed when attached compound undergoes an intramolecular reaction in the presence of acid?
Ketoprofen and ibuprofen both have a propanoic acid substituent. Explain why the identical subunits are synthesized in different ways.
12. You can distinguish epinephrine hydrotartrate from norepinephrine hydrotartrate by? A. Water solubility B. Reactions of oxidation with iodine at different pH C. Reactions in general alkaloid precipitation reagents D. Reactions with iron(III) chloride E. Reactions in Fehling's reagent.
Draw the products of the attached reactions with organometallicreagents.?
Describe the reaction where benzil is prepared by the oxidation of an a-hydroxyketone, benzoin and uses nitric acid to preform oxidation.
is the carbon from the C=O of an aldehyde more reactive or the carbon of the C=N-Imine and why? Dont
The formation of cyanohydrin from a ketone is an example of A. electrophilic addition B. nucleophilic addition C. nucleophilic substitution D. electrophilic substitution E. none of the above
Which of the following method is the best method for the synthesis of propanoic acid A.) Method: Fischer esterification, Reactant: HCl, Substrates: Methanol & ethanoic acid B.) Method: Haloform reaction, Reactants: Br₂ & NaOH, Substrate: Propanone C.) Method: Oxidation, Reactant: KMnO₄, Substrate: 3-hexene D.) Method: Hydrolysis of Cyanohydrins, Reactant: HCN & HCl, Substrate: Propanone E.) None of the given choices
Treatment of ethyl acetoacetate with NaOEt (2 equiv) and BrCH2CH2Br forms compound X. This reaction is the rst step in the synthesis of illudin-S, an antitumor substance isolated from the jack-o’-lantern, a poisonous, saffron-colored mushroom. What is the structure of X?
Which base would be best for promoting elimination over substitution? a. H20 b. CH3O- c.(CH3)3CO- d. CN-
Synthesising menthone is an exothermic process that includes a reflux procedure. Mark the correct statements. * A- The reflux process enables us to transfers energy to the reaction mixture for an extended period of time without loss of solvent or reagents. B- The reflux process increases the rate of the oxidation of menthol. C- The reflux process increases the yield of the oxidation of menthol. D- A water bath can be used in the preparation of menthone because the boiling point of the reaction mixture is below 100°C due to the inclusion of acetone in this mixture.