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- Sickle cell disease is caused by a substitution in the beta globin gene. As a result, one amino acid is different in the mutant protein. Which of the following region is likely to be affected in the sickle cell allele? A. The promoter region B. The 5' UTR region C. The coding region D. The 3' UTRIn the paper we read at the beginning of the term the coat color differences in the beach mice were driven by change in the melanocortin-1 (MCR-1) gene between the color morphs. Based on this information what can you conclude about the mutation causing the color change? a. It is a nonsynonymous substitution. b. The mutation is considered silent. c. The mutation is a transition. d. It is a synonymous substitution.What kind of mutation normally has no consequence? please explain the answer a.transversions b.insertion c.silent d.nonsense
- Tautomerization: A. Causes frameshift insertions B. Causes frameshift deletions C. Results in permanent chemical changes in nitrogenous bases D. Cause transition mutations E. Cause transversion mutationsXeroderma pigmentosum is a genetic disease caused by an error in the nucleotide excision repair process that fixes damage to DNA by ultraviolet light. Studies have shown that it can result from mutations in any one of seven genes. What can you infer from this finding? A) There are seven genes that produce the same protein B) These seven genes are the most easily damaged by ultraviolet light. C) There are seven enzymes involved in the nucleotide excision repair process. D) These mutations have resulted from translocation of gene segments.a) What dipeptide is produced from the following segment of DNA: AGAGAT? (b) What happens to the dipeptide when a point mutation occurs and the DNA segment contains the sequence ATAGAT instead?
- You used agarose gel electrophoresis to separate DNA fragments of different size and the experiment worked well. However, you wanted to re run the experiment but this time you made the gel with a higher percentage of Agarose. How might this affect your results compared to the first run? a. There would be no difference between the runs since it is the current, not the agarose that causes migration. b. The higher concentration of agarose would cause the DNA to break apart. c. You can't predict how the concetration of agarose would affect migration. d. The DNA fragments would migrate further down the gel than they did the first time. e. The DNA fragments wouldn't migrate as far down the gel as they did the first time.A mutagen changes a C-G basepair in the genome to an A-T basepair. This is an example of... A different mutagen changes a C-G basepair in the genome to a T-A basepair. This is an example of... a. transition b. inversion c. transversion d. epigeneticMatch each term with the most suitable description. ___ DNA profile a. GMO with a foreign gene ___ Ti plasmid b. alleles commonly contain them ___ cDNA synthesis c. a persons unique collection of short tandem repeats ___ SNP d. requires reverse transcriptase ___ transgenic e. cuts DNA ___ restriction enzyme f. used in plant gene transfers
- I mutation occurs such that the sequence now reads: CTA CTT TTT. A) Transcribe the short DNA sequence. B) translate this short DNA sequence. C) what type of point mutation is this? A mutation occurs such that the sequence now reads: CTA GTC TTT. 1)transcribe this short DNA sequence. 2. Translate this short DNA sequence. 3. What type of point mutation is this?Match the E. coli mismatch repair enzyme on the left with the appropriate function on the right. MutS MutH MutL a. facilitates the looping of the region of DNA to be replaced b. distinguish between parental and newly-synthesized DNA c. locates mismatches in the DNAIn nucleotide excision repair in E. coli, the function of the UvrA/UvrB complex is toa. detect DNA damage.b. make cuts on both sides of the damage.c. remove the damaged piece of DNA.d. replace the damaged DNA with undamaged DNA.