A mutagen changes a C-G basepair in the genome to an A-T basepair. This is an example of... A different mutagen changes a C-G basepair in the genome to a T-A basepair. This is an example of... a. transition b. inversion c. transversion d. epigenetic
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A mutagen changes a C-G basepair in the genome to an A-T basepair. This is an example of...
A different mutagen changes a C-G basepair in the genome to a T-A basepair. This is an example of...
a. transition
b. inversion
c. transversion
d. epigenetic
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- A biology professor at a prestigious university stated to his introductory class that "Today, a basic understanding of DNA and genetics is as important as a basic understanding of computers and the internet."Based upon what you have learned about DNA and gene expression in this module, how could you make a case to support this statement?You are an expert in DNA-repair mechanisms. You receive a sample of a human cell line derived from a woman who has symptoms of xeroderma pigmentosum. You determine that she has a mutation in a gene that has not been previously associated with XP. How is this possible?Genome comparisons have suggested that mouse DNA has mutated about twice as fast as human DNA. What is a possible explanation for this discrepancy? a. Mice are much smaller than humans. b. Mice live in much less sanitary conditions than humans and are therefore exposed to a wider range of mutation-causing substances. c. Mice have a smaller genome size. d. Mice have a much shorter generation time.
- In the treatment of cancer, the basis for many types of chemotherapyand radiation therapy is that mutagens are more effective at killingdividing cells than nondividing cells. Explain why. What are possibleharmful side effects of chemotherapy and radiation therapy?Discuss the times in a person’s life when it is most important toavoid mutagens. Which parts of a person’s body should be the mosthighly protected from mutagens?Which of the following examples is likely to be caused by asomatic mutation?A. A purple flower has a small patch of white tissue.B. One child, in a family of seven, is an albino.C. One apple tree, in a very large orchard, produces its apples 2weeks earlier than any of the other trees.D. A 60-year-old smoker develops lung cancer.
- In the cancer gene detection lab, a restriction enzyme is added to the p53 genes taken from different locations in the person's body; this restriction enzyme cuts at the location of the mutation (if there is one present). When the enzyme is added to the p53 genes from the tumor, this will result in ____ fragments, and _____ bands on an electrophoresis gel when the DNA fragments separate out.During an Ames test, what does it mean when S. typhimurium is his+? A. The sample is completely safe for humans B. The sample is safe for humans but has a chance to be a mutagen C. The sample is not safe for humans and is considered a mutagen D. The sample is not safe and is hypothetically a mutagenA. What is the pathogen that is attacking bananas today?b. Why is this especially problematic in Africa? C. Why do we expect to lose the war with this pathogen?d. What is random mutagenesis?
- A chemist synthesizes four new chemical compounds in the laboratory and names them PFI1, PFI2, PFI3, and PFI4. He gives the PFI compounds to a geneticist friend and asks her to determine their mutagenic potential. The geneticist finds that all four are highly mutagenic. She also tests the capacity of mutations produced by the PFI compounds to be reversed by other known mutagens and obtains the following results. What conclusions can you make about the nature of the mutations produced by these compounds? Reversed by Mutations produced by 2- Aminopurine Nitrous acid Hydroxylamine Acridine orange PFI1 Yes Yes Some No PFI2 No No No No PFI3 Yes Yes No No PFI4 No No No YesSickle cell disease is caused by a substitution in the beta globin gene. As a result, one amino acid is different in the mutant protein. Which of the following region is likely to be affected in the sickle cell allele? A. The promoter region B. The 5' UTR region C. The coding region D. The 3' UTRthe most efficient general strategy for whole genome sequencing is ? (a) double the coding sequence after sequencing the proteins (b) shotgun sequence and assemble based on overlaps (c) identify mutations that affect glycolysis (d) obtain recombinant DNA clone maps before starting the sequencing (e) obtain comprehensive SNP maps before determining the order of DNA clone
