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Which of the following neurotransmitters is associated
with inhibition exclusively?
a. GABA
b. acetylcholine
c. glutamate
d. norepinephrine
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- Flaccid paralysis (resulting from the failure of muscles to contract), induced by the neurotoxin tubocurarine, occurs when this poison blocks the binding of: the inhibitory neurotransmitter melatonin to post-synaptic bicarbonate channels the excitatory neurotransmitter glutamate to post-synaptic calcium channels the excitatory neurotransmitter acetylcholine to post-synaptic sodium channels the inhibitory neurotransmitter glycine to post-synaptic chloride channels the excitatory neurotransmitter serotonin to post-synaptic potassium channelsIn cholinergic neurotransmission, inhibition of the choline transporter will affect the normal synthesis and release acetylcholineTRUE OR FALSEThere is a toxin extracted from pufferfish called tetrodotoxin (TTX), which completely inhibits (blocks) voltage-gated sodium channels. In low doses it can cause a slight numbness (people eat contaminated pufferfish sometimes!), in high doses it is lethal. Why is this the case? It prevents glutamate uptake and reuptake, causing seizures in the brain Ob. It causes excess neuronal activity, leading to excitotoxicity and cell death It destroys myelin around axons, slowing action potential propagation It prevents action potentials from being initiated, stopping all synaptic transmission O 0 o o
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- Identify the inhibitory neurotransmitter which opens chloride ion channels. gamma amino butyric acid acetylcholine tubocurarine strychnine glutamate Spastic paralysis (resulting from the failure of muscles to relax), induced by the neurotoxin strychnine, occurs when this poison blocks the binding of: the excitatory neurotransmitter acetylcholine to post-synaptic sodium channels the excitatory neurotransmitter glutamate to post-synaptic calcium channels the excitatory neurotransmitter serotonin to post-synaptic potassium channels the inhibitory neurotransmitter glycine to post-synaptic chloride channels the inhibitory neurotransmitter melatonin to post-synaptic bicarbonate channelsName three ways to stop the effect of a neurotransmitteron the postsynaptic membrane. Give an example of each.The following compounds exhibit little to no adrenergic receptor function. Consider what components of adrenaline and noradrenaline are necessary for their action as agonists in light of this knowledge. Explain your response. Assume that the pH of the body is 7.
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