Which of the following types of drugs will have maximum oral bioavailability? A. Drugs with high first-pass metabolism. B. Highly hydrophilic drugs. C. Largely hydrophobic, yet soluble in aqueous solutions. D. Chemically unstable drugs. E. Drugs that are P-glycoprotein substrates.

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter14: Antineoplastic Drugs
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Which of the following types of drugs will have maximum
oral bioavailability?
A. Drugs with high first-pass metabolism.
B. Highly hydrophilic drugs.
C. Largely hydrophobic, yet soluble in aqueous
solutions.
D. Chemically unstable drugs.
E. Drugs that are P-glycoprotein substrates.

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