Which of the gastrointestinal side effects is not usually seen with glucocorticoid use?A. Peptic ulcer diseaseB. Gastrointestinal bleedingC. HemorrhoidsD. PancreatitisE. Abdominal bloating

Essentials of Pharmacology for Health Professions
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ChapterCRE2: Comprehensive Review Exam For Part 2
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Which of the gastrointestinal side effects is not usually seen with glucocorticoid use?
A. Peptic ulcer disease
B. Gastrointestinal bleeding
C. Hemorrhoids
D. Pancreatitis
E. Abdominal bloating

Expert Solution
Step 1

Glucocorticoid - Glucocorticoid is type of steroid hormone. It is secreted by the adrenal glands of our body. The receptors for this hormone are present in almost every animal cell. Glucocorticoid performs various functions. These are:

1. Immunosuppression

2. Anti-inflammatory

Gastrointestinal Tract - GI tract - GI tract is a series of hollow organs that starts from the mouth of the body and ends at the anus. Its a long continuous passage. It includes various organs. These are:

1. Mouth

2. Esophagus

3. Stomach

4. Small Intestine

5. Large Intestine

6. Anus

Step 2

Gastrointestinal side effects are those side effects which effects the organs of the GI tract and GI system. These are GI side effects:

A. Peptic ulcer disease - Peptic ulcer is a condition in which painful sores or ulcers are formed in the lining of the stomach or small intestine. Generally, stomach and small intestine are protected from the effects of acid by thick mucous layer.


B. Gastrointestinal bleeding - GI bleeding is a kind of disorder of the GI tract. In this disorder, the organs of the GI tract gets wounded and starts to bleeds. This blood appears either in the stool or in the vomit.


C. Hemorrhoids - Hemorrhoids is a kind of disease which includes swollen or inflamed veins in the rectum or anus. There are two types of hemorrhoids:                                                                                                                                i) Internal Hemorrhoids - It is normally painless but causes bleeding.                                                                              ii) External Hemorrhoids  - It is painful.


D. Pancreatitis - Pancreatitis is a kind of disease which means inflammation in the pancreas. Pancreas is an important organ which helps in the process of digestion. It inflammation occurs in pancreas then there will be a problem in digestion.


E. Abdominal bloating - Abdominal bloating is a condition in which there is a build up of gas in the abdomen and intestine. This condition occurs when the GI tract is filled with gas or air. The stomach feels like tight and swollen.

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