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Which three factors are crucial in the diagnosis of genetic defects in the fetal stage? What do you think weighs the most?
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- Explain the difference between X-linked recessive traits and X-linked dominant traits. What are the possibilities that a female child will be affected and express each of the traits?What conditions can be detected using fetal ultrasonography, amniocentesis, and chorionic villi sampling? What are the advantages of noninvasive prenatal tests?Why do most cases of Down syndrome originate from the mother? And how is this linked to maternal age ?
- Suppose you are a carrier of fragile X syndrome and want to have children. Would you choose pregnancy, adoption, or surrogacy? If you became pregnant, would you opt for prenatal diagnosis? Explain your decisions.Give a brief explanation on how chromosomal abnormalities affect prenatal pregnancy or birth.At which stage of development does XCI initially occur?
- What mode of inheritance is exhibited? ____________________________________ Using the letters, Aand a, give the genotype of the following individuals: I1: __________ II4: __________ III9: __________ I2: __________ II5: __________ III14: __________ II3: __________ II8: __________ IV18: __________Why doesn’t the father (II-1) have the disease breast cancer? What is the formal name for an individual having the gene but not showing the trait?Why does theheterozygote have an advantage?