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Which of the following conditions is most likely to force a muscle cell to
- Glyceraldehyde-3-phosphate dehydrogenase deficiency
- Lactate dehydrogenase deficiency
-Pyruvate kinase deficiency
-Aldolase deficiency
- Cytososic Glycerol-3-phosphate dehydrogenase deficiency
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- Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinaseWhat type of regulation would be expected when anaerobic metabolism is occurring in the muscle? Select all that apply. 1. Activation of pyruvate dehydrogenase kinase 2. Increased levels of calcium to activate pyruvate dehydrogenase phosphatase 3. Phosphorylation of pyruvate dehydrogenase 4. Inhibition of pyruvate dehydrogenase complex 5. Increased levels of NADH to activate citrate synthase 6. Increased levels of NADH to inhibit alpha-ketogluterate dehydrogenase complex 7. Increased levels of acetyl CoA to activate pyruvate carboxylase for gluconeogenesiswhich of the following is not true for a muscle that is forced to metabolize glucose anaerobically ? - The cells breakdown glucose faster - The cells produce less ATP per mole of glucose - The cells metabolize glucose to lactate - The activity of the cytosolic gycerol-3-phosphate dehydrogenase will be required for the muscle to sustain glycolysis - The muscle quickly experiences fatigue if it is deficient in the enzyme lactate dehydrogenase
- During glycolysis, the major energy generating step involves: pyruvate kinase phosphoglycerate kinase Phosphofructokinase glyceraldehyde-3 -dehydrogenaseWhich of the listed glycolytic enzymes adds a phosphate group to ADP to produce ATP? 1.) pyruvate kinase 2.) hexokinase 3.) phosphofructokinase-1 4.) pyruvate dehydrogenase 5.) phosphexose isomerase 6.) lactate dehydrogenaseWhich of the following is NOT a component of the pyruvate dehydrogenase complex? a. dihydrolipoyl dehydrogenase b. dihydrolipoyl transacetylase c. pyruvate dehydrogenase d. dihydrolipoyl catalase
- Which glycolysis reactions are catalyzed by the following enzymes?(a) Pyruvate kinase(b) Glyceraldehyde 3-phosphate dehydrogenase(c) Hexokinase(d) Phosphoglycerate mutase(e) AldolaseWhich of the following is a negative regulator of the pyruvate dehydrogenase complex (PDC)? 1. acetyl CoA 2. ADP 3. pyruvate 4. citratewhich enzyme uses ATP to phosphorylate a substrate during gluconeogenesis? -Hexokinase - Phosphofructokinase 1 - Glyceraldehyde-3-phosphate dehydrogenase - Phosphoglycerokinase - Pyruvate Kinase
- iodoacetate is an irreversible inhibitor of glyceraldehyde-3-phosphate dehydrogenase. which of the following is the expected outcome of the exposure of a cell to iodoacetate - Cellular resiration will stop if the cell solely depends on glucose as fuel - The rate of cellular respiration will increase - The reoxidation of coenzymes will noy be affected , but the efficiency of oxidative phosphorylation will be diminished - There will be no effect on cellular respiration as long as the cell has a large glucose reserve -The cell sill not be able to reoxidize the reduced coenzymesWhich of the following is the correct summary of the anaerobic breakdown of glucose in the skeletal muscle? Glucose + ADP + Pi ⟶ lactate + ATP Glucose + 2ADP + 2Pi ⟶ 2 lactate + 2ATP Glucose + 2ADP + 2Pi + 2NAD+ ⟶ 2 pyruvate + 2ATP + 2NADH + 2H+ Glucose + ADP + Pi ⟶ pyruvate + ATP Glucose + 2ADP + 2Pi ⟶ 2 pyruvate + 2ATPCHOOSE THE CORRECT LETTER When glycogen is synthesized in both the liver and muscle, all the following are true, EXCEPT A.Glucose is transferred from UDP-glucose to a growing glycogen molecule by glycogen synthase.B. Phosphoglucomutase converts glucose 6-phosphate to glucose 1-phosphateC. Glucose 6-phosphate is converted to glucose by a phosphatase.D.Glucose 1-phosphate is activated by UDP-glucose pyrophosphorylase to produce UDP-glucose and PPi.