Why is HIV protease a good target for anti-HIV therapy and drug discovery?

Q: Why is knowing about how COVID-19 virus works important?

A: Coronavirus causes disease called COVID-19. CoV coronaviruses are large family of viruses which are…

Q: What is HAART in the treatment of HIV infection? What are the targets of the drugs that are…

A: HIV( human immunodeficiency virus) causes AIDS (acquired immunodeficiency syndrome) in humans. It is…

Q: Some viral detection techniques involve a serological assay. This assay looks for the presence of…

A: The viruses are infectious agents, which are capable of infecting the cells and cause diseases. The…

Q: Are the HIV-1 protease inhibitors transition state analogs? Why or why not?

A: A drug that resembles the substrate portion of transition state of a reaction normally catalyzed by…

Q: What is HIV-protease ?

A: HIV-1 protease (PR) is a retroviral aspartyl protease , an enzyme involved with peptide bond…

Q: What is unique about Z-DNA that might make it a specific target during viral infection?

A: Z-DNA is a type of double-helical structure of DNA. It shows a left-handed double helical structure…

Q: What does the enzyme reverse transcriptase do and why is it agood target for anti-HIV drugs?

A: A virus is a submicroscopic infectious agent. It replicates only inside the living cells of an…

Q: What is the action mechanism of the antiretroviral drugs called protease inhibitors which are used…

A: A number of antiretroviral agents are used to treat HIV, although no complete cure for the disease…

Q: Why have attempts to find a vaccine against HIV been unsuccessful?

A: Human Immunodeficiency Viruses are types of lentivirus which causes immunosuppression in humans and…

Q: What are the evolutionary origins of HIV-1 and HIV-2?

A: HIV (Human immunodeficiency virus) belongs to a family of retroviruses, all of which have RNA as…

Q: How is AZT a competitive inhibitor of HIV reverse transcriptase?

A: A vital early stage in the HIV life cycle is the reverse transcription of the viral RNA genome into…

Q: an infection of HIV in a patient mutates so that it changes the genes involved in attachment, which…

A: The body’s immune system is affected by HIV which can lead to AIDS. HIV stands for human…

Q: Why might an HIV/AIDS vaccine actually give some people a false sense of security?

A: Vaccination is the process by which vaccines are provided to individuals with an aim of stimulating…

Q: Explain the human immunodeficiency virus (HIV)?

A: The human immunodeficiency(HIV) virus is a virus that attacks cells that facilitate the body fight…

Q: What are adenovirus vectors in gene therapy ?

A: Gene is a particular segment of deoxyribose nucleic acid (DNA) that is responsible for the…

Q: What are the differences of replication of virus and replication of HIV?

A: Virus It is a submicroscopic infectious agent. It can replicate only inside the living cells.…

Q: One of the first and most important targets for drugs to fight infection with HIV (a retrovirus) is…

A: Human immunodeficiency virus (HIV) is a retrovirus that contains single-strand RNA genome. It…

Q: What is the role of tRNAlys in the HIV replication cycle?

A: Transfer RNA is a small RNA molecule that plays a key role in protein synthesis, tRNALys is the tRNA…

Q: What distinguishes a retrovirus from an LTR transposon, and how is this difference enabled?

A: LTR retrotransposons are class I transposable elements characterized by the presence of long…

Q: How many Covid-19 vaccines have been developed? How do the COVID-19 vaccines work? And how do we…

A: COVID-19 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2…

Q: What is the continuous challenge that the influenza virus presents toscientists and public health…

A: Influenza refers to an acute respiratory illness that spreads from zoonotic reservoirs among aquatic…

Q: is HIV in humans different than HIV in rabbits? or the same.

A: Human Immunodeficiency Virus or HIV is a retrovirus which causes Acquired Immuno Deficiency Syndrome…

Q: Why is gap repair synthesis needed during HIV DNA integration?

A:

Q: Why is an HIV vaccine needed? Describe and explain in detail

A: The human immunodeficiency virus (HIV) is a retrovirus that contains a single stranded RNA as its…

Q: How does the enzyme reverse transcriptase violate the central dogma of molecular biology in HIV

A: A reverse transcriptase (RT) is an enzyme that converts an RNA template into complementary DNA…

Q: Why is the detection of viral RNA not equivalent to a high risk transmission method?

A: The detection of the viral RNA, detection of infectious virus and equivalent transmission risk are…

Q: How is HIV different than the flu virus?  Why can we make vaccines for some viruses but not all?

A: The above question explanation is given below.

Q: What is the percentage of humans that are resistant to HIV? What makes them resistant?

A: HIV - is also known as Human immunodeficiency virus infection .

Q: During HAART therapy for Human Immunodeficiency Virus (HIV), what are the rationale and mechanisms…

A: HAART:  Multiple antiretroviral medications are typically used in the treatment of HIV/AIDS in order…

Q: How the use of the nucleic acid vaccine gives protection against diseases like COVID-19. Please…

A: Vaccines are usually prepared using a minimal amount of the weakened or the death form of the germs…

Q: Please help explain this LAPTM5 Transport HIV-1 Env to the lysosome for degradation

A: Answer

Q: Which of the following is not a component of HIV?

A: Human immunodeficiency viruses (HIV) are two Lentivirus (a retrovirus subgroup) species that infect…

Q: How do interleukins exert its therapeutic benefits inside the body By inhibiting tumor growth and…

A: Correct answer is B  Because interleukin stimulation the immune response and increase the number of…

Q: As a nursing student how can you contribute to avert the spread and effects of COVID-19?

A: The whole world is suffering from this covid-19 and as per the rules and standards from the…

Q: What part of the HIV lifecycle is disrupted by the drugs indinavir and amprenavir?

A: The use of drugs for treating HIV cannot cure it but they act by preventing the virus from making…

Q: Tat and Rev proteins are required for HIV replication. What are their roles and why are they…

A: Introduction Human immunodeficiency viruses (HIV) are two types of Lentivirus (a type of retrovirus…

Q: How is human immunodeficiency virus (HIV) resistant to disinfectants and antiseptics?

A: Antimicrobial agents that are used to destroy or kill the pathogenic microorganism on the surface of…

Q: Leber amaurosis

A: Leber amaurosis It is a eye disease that primarily affects the retina. It is an congenital disorder…

Q: What role does the Env trimer play in HIV infection?

A: The HIV-1 envelope glycoprotein (Env) trimer is located on the surface of the virus and is the…

Q: What is the function of each of the following HIV products: gp120, reverse transcriptase, and…

A: HIV is a virus which that attacks the immune system. HIV components play a vital role during the…

Viral Infections

Viruses are abundantly found, minute entities that have genetic material enclosed within a protein coat. The proteinaceous material enclosing the genetic material of the virus is called a capsid. The genetic material could be either DNA (deoxyribonucleic acid) or RNA (ribonucleic acid). A virus is too minute to be looked at with naked eyes and therefore visualized with the help of a microscope. They are acellular entities that require a host for processes, such as replication, transcription, translation and multiplication. Plants, animals, and bacteria act as host wherein the virus reproduce. Viruses cannot multiply outside the host's body and thus are considered nonliving outside the host body.