Write the inhibitors of following metabolic pathways 1. glycolysis 2. TCA
Q: Discuss the Anaplerotic reactions of TCA cycle.
A: The term amphibolic is used to describe a biochemical mechanism that includes both catabolism and…
Q: A patient has hemolytic anemia. In describing her recent activities, she mentioned that she ate fava…
A: There is a direct link between the G6PD deficiency and hemolytic anemia in the patients.
Q: In the following diagram of glycolysis. Identify the steps that are amphibolic, taking place in both…
A: The biochemical processes or pathways that serve both catabolic and anabolic functions are known as…
Q: Compare the transketolase and transaldolase reactions in terms of substrates, products, mechanism,…
A: Transaldolase is an enzyme catalyzing the conversion of sedoheptulose-7-phosphate and…
Q: Hypercholesterolemic individuals taking statins are sometimes advised to take supplements of…
A: The high cholesterol level in the blood of the body is referred to as hypercholesterolemia. It is an…
Q: Before b-oxidation, fatty acids are converted to theirCoASH derivatives. Explain why this reaction…
A: Beta oxidation is a process, during which the fats are broken to produce energy.
Q: With a AGO'of -16.7 kJ/mol, the reaction catalyzed by hexokinase is considered to be at equilibrium…
A: Standard free energy change indicates the portion of the total energy of a system that is…
Q: To understand the entire glycolytic pathway better, kindly complete the table Structural activator…
A:
Q: The metabolism of alcohol pathway is showed in the figure characterized by biotransformation of:…
A: Metabolism- The primary enzyme involved in the metabolism of alcohol is ADH( Alcohol dehydrogenase)…
Q: The negative impact of PKU can be reduced by stimulation of alternative pathways of phenylalanine…
A: All the genes in the body are present in the DNA of the cell. these genes are a triplet codon of…
Q: Two of the bypass reactions of gluconeogenesis involve: a phosphorylation of ADP using phosphate…
A: Introduction: Gluconeogenesis is the synthesis of glucose or glycogen from a non-carbohydrate…
Q: Oxidation Reduction chemiosmosis acetyl coenzyme Give the definition
A: Oxidation:In terms of oxygen transfer, oxidation is the gain or addition of oxygen but in terms of…
Q: In the table below, choose the appropriate metabolic processes for each scenario: Metabolic…
A: Metabolic processes are constantly taking place in the body. Metabolic Processes Process that…
Q: Acetyl CoA is essential for the synthesis of chole Tricarboxylic acid cycle operates only under ana
A: answer: B statement 1 is true statement 2 is false
Q: Identify the 4 steps of gluconeogenesis that are different from glycolysis. Write the reactants,…
A: Gluconeogenesis (GNG) is a metabolic pathway that results in the generation of glucose from certain…
Q: Give one example of a futile cycle that could occur in fat/ketone body metabolism and how it is…
A: Futile cycle occurs when two cycles run simultaneously but in opposite directions which ultimately…
Q: Fluoride is an inhibitor of which of the following glycolytic enzymes? A. Glyceraldehyde 3 po4…
A: Glycolysis is the process of breakdown of glucose into pyruvate to generate energy.
Q: A trequently found genetic disease is mutation in the medium chain acylCoA dehydrogenase. This leads…
A: Beta-oxidation is oxidation of fatty acid on the beta carbon. Medium chain acyl CoA dehydrogenase…
Q: 1. Briefly explain why an individual with Aldolase B deficiency will suffer from hypoglycemia upon…
A: Introduction Aldolase B (fructose-1, 6-bisphosphate aldolase) is an enzyme important in fructose…
Q: Define the following terms:a. adipocyteb. MCADc. ACPd. a-oxidatione. odd-chain oxidation
A: Metabolism is the set of chemical reaction that is responsible for carryi8ng out essential functions…
Q: Order the following TCA cycle metabolites in the order they appear in the cycle. Not all answers…
A: Tricarboxylic acid or TCA cycle is also known as the Krebs cycle and is an important part of aerobic…
Q: Discuss briefly but concisely the importance of the following metabolic pathway. D.…
A: Metabolism is the set of chemical reactions that keep organisms alive. Food is broken down into…
Q: Conversion of amino acid nitrogen into urea by the liver for excretion normally involves all the…
A: The end products of amino acid and nucleic acid metabolism meet the urea cycle. The urea cycle is…
Q: Select the following enzymes that utlize a mechanism involving covalent catalysis. Select ALL that…
A: Covalent catalysis: The process of covalent catalysis involves the formation of covalent bonds…
Q: With the aid of a diagram discuss the three genetic disorders associated with the…
A: A hereditary condition in human associated with the instability to metabolize the amino acid…
Q: Match the following descriptions with their corresponding metabolic processes
A: The metabolic mechanism that transforms glucose (C6H12O6) to pyruvic acid (CH3COCOOH) is known as…
Q: which of the following functions matches with the coenzyme functions: a.) facilitate redox…
A: Organic compounds often B vitamin derivative that combines with an inactive enzyme to form an active…
Q: Enumerate the different enzymes involved in the following carbohydrate metabolic pathways. Show…
A: Glycogenolysis is the pathway, which breaks down the glycogen molecules that are stored in the…
Q: In own words, give 5 or more reasons why most of the clinical features of the diseases…
A: Mitochondria are an essential component of eukaryotic cells, and their failure has been linked to a…
Q: 1.Enumerate the enzymes of the alpha ketoglutarate dehydrogenase complex and write its mechanism of…
A: α-ketoglutarate dehydrogenase is an enzyme present in the mitochondria. It catalyzes the important…
Q: Suggest a name for an enzyme that catalyzes each of t a.) Oxidation of nitrite b.) Decarboxylation…
A: An enzyme is a substance that acts as a catalyst in living organisms, regulating the rate at which…
Q: Designate the reactions catalyzed by the following enzymes:a. aldolaseb. enolasec. hexokinased.…
A: Enzymes function as biological catalysts by increasing the rate of reactions. They bind to reactants…
Q: draw the products formed when triacylglycerol is treated with: a. H2O, H+
A: Triacyl Glycerol is a complex compound formed when fatty acids esterified to Glycerol at three…
Q: Select the correct statement for pyruvate dehydrogenase (a) Catalyses oxidative decarboxylation (b)…
A: Pyruvate dehydrogenase: An enzyme that catalyzes the reaction of pyruvate and a…
Q: Select which of the following enzymes unique to glycolysis are also sites of regulation for…
A: Glycolysis is also known as Embden-Meyerhof pathway. It occurs in cytosol and converts glucose into…
Q: make a flow chart of a drug and show its metabolism noting if there are active metabolites where…
A: Drug metabolism occurs primarily in liver. Although drug is inactivated by metabolism, some drug…
Q: One of the enzymes involved in glycolysis, aldolase, requires Zn2+ for catalysis. Under conditions…
A: When an enzyme is deficit of zinc it would become inactive and not be able to perform catalysis.…
Q: d) Glucose-6-phosphatase e) Glutathione reductase
A: Gout: a. It is a hereditary and metabolic disease resulting from defective uric acid metabolism. b.…
Q: Discuss briefly but concisely the importance of the following metabolic pathway. H.B-oxidation of…
A: Introduction: Fatty acids from the diet or through degradation of triglycerides stored in the…
Q: In Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C.…
A: Pyruvate is made from the glycolysis of glucose, glycolysis breaks glucose into two pyruvate.…
Q: Discuss the metabolic control for HMG CoA reductase synthesis and activity
A: HMG CoA (3-hydroxy-3-methyl-glutaryl-coenzyme A) reductase, or HMGCR, is the primary rate-limiting…
Q: Briefly explain the mechanism involved when an individual with glucose 6-phosphate dehydrogenase…
A: The NADPH (nicotinamide adenine dinucleotide phosphate) is the source of reducing energy for the…
Q: Discuss each method of regulating phosphofructokinase 1 (indicated by the blue circle) as shown…
A: One of the most essential glycolysis regulatory enzymes is phosphofructokinase-1 (PFK-1). It's an…
Q: Select the following enzymes that utilize a mechanism where an enediol intermediate is formed. Check…
A:
Q: Metabolism can be broken down into two types of processes: those which are anabolic and those which…
A: Metabolism is essential for the generation of the molecules required for the survival of the cell or…
Q: Diazepam is converted in vivo to an active metabolite Oxazepam. Explain metabolic transfomation of…
A: Diazepam is an anxiolytic medication belong to the family of benzodiazepine. It is used for the…
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- What is the most dangerous adverse effect following use of biguanides?A. Lactic acidosisB. HypoglycaemiaC. Diabetic ketoacidosisD. HyperosmolalityE. HyperglycaemiaDescribe the role of ethanol in cellular energy supply, the metabolism of ethanol (alcohol), the regulation of its metabolism and the disease conditions associated with its metabolism especially - hypoglycemia, ketoacidosis, hepatic steatosis, Vitamin deficiency, and acetaldehyde toxicity (you should feel free to discuss other diseases that are directly related to ethanol metabolism).Discuss disease states caused by the malfunctioning of glycolysis, PDH and the TCA cycle.
- Define the following terms:a. Cori cycleb. glucagonc. glucose-alanine cycled. hypoglycemiae. antioxidantDefine the following terms:a. adipocyteb. MCADc. ACPd. a-oxidatione. odd-chain oxidationIndicate what will happen (increase, decrease or no effect) to the activity of enzyme or rate of the metabolic pathway given the following conditions: 1. release of glucagon in the blood to the activity of carnitine acyl transferase 1 2. phosphorylation of acetyl CoA carboxylase 3. low [carbon dioxide]/[oxygen gas] ratio to the oxygenase activity of RuBisCO
- Explain how excessive ketone bodies may form in the following: During starvation In patients with diabetes mellitusIt has been suggested that a high-sugar diet may lead to non-alcoholic fatty liver disease. Explain?Match the bold specific genetic metabolic disorders to their category: adrenal hyperplasia Albinism Cystinuria Galactosaemia Phenylketonuria Pompe Wilson Disease Chromosomal abnormality Excessive amounts of metabolites in a metabolic pathway Storage disease Disrupted regulatory system Disrupted Vitamin and/or co-factor absorption or processing Transport disorder Accumulation of substrates in a metabolic pathway Absence of end product
- Choose which enzyme is likely deficient based on the symptoms described below: Elevated blood lactate, alanine and pyruvate a) lactate dehydrogenase d) citrate synthase c) pyruvate dehydrogenase d) pyruvate kinaseAlcoholism is often associated with hepatomegaly (due to lipid deposits) and lactic acidosis. Explain the metabolismNonalcoholic fatty liver disease has been linked to a sugary diet. Explain?