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You are studying a single-gene locus with two alleles in a population that is in Hardy–Weinberg equilibrium. Examination of a large sample of individuals from the population reveals there are six times as many heterozygotes as there are homozygote recessive individuals in this population. What is the frequency of the recessive allele?I don't know how to start his calculation with just a ratio of 6:1 I found an answer online that says the frequency of q=0.25 but the calculations (below) don't make sense to me. Please help me. What is the answer and how do I get to it?Hardy-Weinberg equation p2+2pq+q2=12pq/q2= 6/12p= 6q2(1-p)= 6q2-2q=6qq=0.25

Question

You are studying a single-gene locus with two alleles in a population that is in Hardy–Weinberg equilibrium. Examination of a large sample of individuals from the population reveals there are six times as many heterozygotes as there are homozygote recessive individuals in this population. What is the frequency of the recessive allele?

I don't know how to start his calculation with just a ratio of 6:1 I found an answer online that says the frequency of q=0.25 but the calculations (below) don't make sense to me. Please help me. What is the answer and how do I get to it?

Hardy-Weinberg equation p2+2pq+q2=1

2pq/q2= 6/1

2p= 6q

2(1-p)= 6q

2-2q=6q

q=0.25

check_circleAnswer
Step 1

In the Hardy-Weinberg equilibrium, the allele frequency and the genotype frequency of the individuals remain the same for the various generations. According to the Hardy-Weinberg equation:

p2 + 2pq + q2 = 1.

Where,

p2 = Frequency of the homozygous genotype (dominant)

q2 = Frequency of the homozygous genotype (recessive)

2pq = Frequency of the heterozygous genotype

Step 2

Here, it is given that heterozygous individuals are 6 times more than homozygous recessive. So the ratio for heterozygous: homozygous recessive is 6:1.

Heterozygous=6xHomozygousrece ssive
2pq-6q2
2p 6q
p 3q
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Image Transcriptionclose

Heterozygous=6xHomozygousrece ssive 2pq-6q2 2p 6q p 3q

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Step 3

According to the Hardy...

(302+230q+q2=
9q2 +6 +q2=
16q21
2-6
=1
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Image Transcriptionclose

(302+230q+q2= 9q2 +6 +q2= 16q21 2-6 =1

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