You have made several mutations in the coding region of the gene coding for the sodium channel and placed them in expression vectors to have the synthetic proteins placed in the membranes of the cultured cells. As a result, the cells no longer contract with the same force as the wild type. why does this occur?

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter37: The Endocrine System
Section: Chapter Questions
Problem 1VCQ: Figure 37.5 Heat shock proteins (HSP) are so named because they help refold misfolded proteins. In...
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You have made several mutations in the coding region of the gene coding for the sodium channel and placed them in expression vectors to have the synthetic proteins placed in the membranes of the cultured cells. As a result, the cells no longer contract with the same force as the wild type. 

why does this occur? 

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