ZHN" [1] O3, then (CH3)2S RSO3H [2] NABH4, CH3OH several steps н Ph н CH30 darunavir

Q: The reaction between 2-iodohexane and ethanol to give a substitution product most likely follows an…

A:

Q: Propose a mechanism and predict the major product. Cl2 hv

A: The reaction between alkanes and Cl2 in presence of light i.e hv is known as chlorination reaction.…

Q: Identify the most basic atom of Q and explain your answer. Propose a mechanism for the conversion of…

A: Since you have asked multiple questions we have answered the first two for you. To get the remaining…

Q: OH H30* он

A: To show the mechanism of the following reaction

Q: 1. 98% H2SO4 Ме OMe Br- -78 °C 2. Li e ČO,Me OMe -78 °C-rt, THF

A: Robinson annulation followed by Quasi-favorskii reaction will give the desired product.

Q: Propose a stepwise mechanism for the following transformation. Me Me Me но Me SOCI2 CI

A: Given conversion,

Q: 3) Draw a plausible mechanism for the following transformation: 0. 0. H³0Ⓡ NO₂

A: In this question we have to tell the product of the reaction and also its mechanism.

Q: Propose a mechanism for the following reaction:

A:

Q: Q11. Provide a mechanism that leads to the major product: NO2 CH NH2 Br Q12. Propose a set of…

A: Q 11. Aromatic Sn2. Q 12. ( see below).

Q: Decytospolides A and Bare fungal natural products that are toxic to some cancer cells, In a…

A: Concept : 1) NaH is used as base for deprotonation.  2) Grignard reagent is used as nucleophile here…

Q: Propose a mechanism for the following conversion ОН + H;0

A: We have given the organic reaction and we have to find the mechanism of the reaction.

Q: 1. Draw a plausible mechanism for the following transformation. H H2SO4 N° + 2H20 + NH2NH2 H

A:

Q: 9. Provide a mechanism for the following transformation: H,Cro, он HO H,O

A: In presence of H2CrO4 , alcohol is oxidised to acid through the formation of aldehyde.

Q: Q. 2 Write all the steps with appropriate reagents for the following transformations. a) `NH2 OC2H5…

A: As per the rules, only the first three questions can be answered. Organic transformations.

Q: (E)-Anethole is the major component of anise oil, which is used as artificial licorice flavoring and…

A: Given:

Q: Draw the product of the following reaction sequence, including stereochemistry. CH3 [1] BH3 [2]…

A: The given reactant is 1-methyl cyclohexene. The product formed from the given reaction is given…

Q: 3. (A) Provide the necessary reagents to accomplish the following transformation. CH2BR CH2OH CH2CH3…

A:

Q: D phmgBr, Etz0. locts OCH3 2) Hz0

A: Given,

Q: Which of the following is a major product of the reaction sequence shown? (1) HO HO (2) CH;CH,M…

A:

Q: 3. Propose a plausible mechanism for the following transformation: OH

A: Organic transformation in acidic medium:

Q: The poison gelsemoxonine can be isolated from the leaves of a plant native to southeastern Asia…

A: Sigmatropic rearrangement: It is a pericyclic reaction in which a sigma bond migrates from one site…

Q: Draw the synthons and synthetic equivalents for the following compounds. a) c) Meo d) b) O2N NO2

A:

Q: ite the structures of A-C and mechanisms of the following reactions. (i) Me2CuLi (i) PhMgBr N' HCI H…

A: In the above reaction, first step is formation of enamine Second step is reaction of Gilman Third…

Q: Draw the product Y of the following reaction sequence. Y was anintermediate in the remarkable…

A: In the given reaction, the nucleophilic attack will takes place and followed by the elimination…

Q: b) Predict a mechanism for the following reaction: Ph. Ph. H,N. Ph Ph H,N

A: Given reaction: We have to write the mechanism of the reaction.

Q: Propose a mechanism for the following reaction:

A: The reaction which is occur between the enolate ion and the carbonyl compound is known as aldol…

Q: Propose a mechanism for the following reaction

A: Aldol reaction: It is a reaction in which carbonyl group reacts with enolate of aldehyde and ketone…

Q: When a cyclic ketone reacts with diazomethane, the next larger cyclic ketone is formed. This is…

A: To draw a mechanism for the below ring-expansion reaction.

Q: 7. Propose a mechanism for the following transformation. H* `NH2

A: In the mechanism of the above reaction ; 1st step involves the protonation  2nd step : attack on…

Q: Fill in reagents A, C, E and compounds B, D in the following transformation. A В C D E CI.

A:

Q: 4) Draw the MAJOR product of the following reactions. Show stereochemistry when appropriate. Circle…

A: We have to give the major products and also tell the type of the mechanism.

Q: Identify R and S in the following reaction sequence, and draw a mechanism for the conversion of R to…

A:

Q: H,0 Cat TSOH но OMe OMe MEOH cat. TSOH -H0

A: Ring opening reaction of epoxides goes through SN2 mechanism.

Q: A Mannich reaction puts a  R R-NCH2 - group on the α-carbon of a carbon acid. Propose a mechanism…

A: For a Mannich reaction to take place the presence of a hydrogen atom at the carbon atom adjacent to…

Q: H,SO4 Нeat

A:

Q: What set of reagents can best accomplish the following transformation? Br A) PCC in CH₂Cl₂ B) NaBD,…

A: The solution is given below -

Q: a) Draw the initial ENOL products for the two reactions below: Reaction 1: Reaction 2: CH₂(CH₂)C=CH…

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Q: In the lab, you are provided with an unknown C, which when reacted with O3 followed by (CH3)2S…

A:

Q: OH CH3 CH3 H,SO4, `CH3 `CH3

A: Since there is lone pair electrons on double bonded O in the reactant. Hence it will take proton…

Q: (a) Strategies the synthesis of the given transformations to ensure no side-product (provide the…

A:

Q: Draw the final major product when Benzene is exposed to the following sequential steps. 1) CH3Br,…

A: Benzene undergoes electrophilic substitution reaction

Q: Reaction of p-cresol with two equivalents of 2-methylprop-1-ene affords BHT, a preservative with…

A:

Q: CH3 + a13- 29°C

A: The key step in this transformation is the formation of a stabilized anion by using pyridine and…

Q: 5.1. Suggest a mechanism for the following transformation and say how you would test it. CI CI OC…

A: The given substrate is an organometallic complex in which the central metal is iridium (Ir). Let us…

Q: Draw the detailed mechanisms for the following transformations. H3C 0CH 3 (1.5 equiv) OCH3 then…

A:

Q: What is the best choice of reagent(s) to perform the following transformation? A. BH3, THF followed…

A: Ozonolysis is an efficient way of oxidizing alkenes into their corresponding aldehydes and ketones.

Q: Propose a mechanism for each of the following reactions:

A: The mechanism for the reaction (a) is shown below.

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.