Osteoporosis is a progressive metabolic bone disease that decreases bone density causing skeletal weakness. Bone is continually being formed and resorbed in the body. Osteoblasts are cells that build and mineralize the organic matrix of bone. Osteoclasts are cells that resorb bone. Normally, bone formation and resorption are closely balanced. Osteoporosis occurs when osteoclasts break down bone at a faster rate than osteoblasts can create it. Osteoporosis is often referred to as a silent disease
Osteoporosis is the disease process by which bone remodeling is altered. This alteration is when old bone is insufficiently replaced by new bone (Cosman et al, 2014). New bone growth peaks in the early 20’s and after this age bone mass is lost faster than generated. The lack of new bone replaced can lead to fractures and deformed skeletal architecture. This alteration occurs with menopause, increased age, or long term use of corticosteroids (Cosman et al, 2014) Often the first sign of osteoporosis
Justification Osteoporosis is commonly known around the world as the numbers continue to increase every year. Osteoporosis is known to cause problems in middle aged women and occasionally effecting some men (1), currently reaching the number of 200million women diagnosed with osteoporosis (2). Arthritis Organisation states that anyone can get osteoporosis but women are about four times more likely than men to develop it, with two main reasons contributing to this fact. For several years after menopause
Osteoporosis is a medical condition that causes the bones to become delicate and breakable due to a loss of tissue, usually caused by hormonal changes and even a deficiency of calcium, which includes vitamin D. If upon a minor fall, or lifting an object the wrong way you may experience a broken bone, that could be a sign of osteoporosis. Although it is true that while people age, they lose bone density, it is not true that everyone will for sure get Osteoporosis. There is no known cure yet for Osteoporosis
risk factor of osteoporosis is higher in people who already have certain medical problems such as cancer and kidney or liver disease. Besides, the risk of fracture is also increase in patients with condition that the high risk of falls such as hemiplegia, lower limb dysfunction and Parkinson’s disease. It has been shown that an initial fracture is a major risk factor for a new fracture as other clinical condition’s fractures can lead to osteoporosis. Overall, osteoporosis is a disease that
Osteoporosis Osteoporosis is a significant health problem that affects more than 25 million women in the United States and potentially 200 million worldwide. This disease is characterized by diminishing the structure of the skeleton (particular the "spongy" bone). This results in an increased risk of fracture. Osteoporosis develops silently over a period of years, eventually progressing to a point where a fracture can easily occur causing pain and disability. This disease is characterized
Osteoporosis is a degenerative disease of the bones generally brought on by the process of aging, unfortunately there can also be a number of underlying or secondary causes; however, preventative care and drug treatments can minimize the severity of this prevalent disease. Osteoporosis has been estimated to affect more than 200 million people worldwide (Bethel, 2015). According to the National Osteoporosis Foundation, 9.9 million Americans have osteoporosis and an additional 43.1 million have low
Osteoprosis Osteoporosis is a condition of decreased bone mass. This leads to fragile bones which are at an increased risk for fractures. In fact, it will take much less stress to an osteoporotic bone to cause it to fracture. The term "porosis" means spongy, which describes the appearance of osteoporosis bones when they are broken in half and the inside is examined. Osteoporosis or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue, leading
Osteoporosis is a disease in which bone tissue is normally mineralized but the mass of bone is decreased and structural integrity of trabecular bone is impaired. Cortical bone becomes more porous and thinner, making bone weaker and prone to fractures. The World Health Organization (WHO)(1994) has defines postmenopausal osteoporosis abased on the bone density. Bone density is based on the number of standard deviations away from the mean bone mineral density of a young adult reference population, a
Systemic glucocorticoids are the leading cause of secondary osteoporosis. Osteoporosis is described by the World Health Organization (WHO) as a ‘progressive systemic skeletal disease characterised by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture’. Oral glucocorticoids are the low bone mass and microarchitectural deterioration main iatrogenic cause of fragility fracture. Relationship between glucocorticoid