Muscarinic acetylcholine receptor M1

‘Electro- and pharmomechanical coupling in the smooth muscle cells of the rabbit ear artery’, Journal of General Physiology, vol. 70, no. 2, pp. 129-148 EDMAN KA & SCHILD HO 1962, ‘The need for calcium in the contractile response induced by acetylcholine

Dementia and it 's types Dementia is a syndrome caused by multiple progressive illnesses that affects memory, thinking, orientation, behaviour, comprehension, calculation, judgement, learning capacity, language, and loss of motivation and emotional control. The syndrome is characterized by Alzheimer’s disease, dementia with lewy bodies, vascular dementia, and frontotemporal dementia. Dementia mainly affects older people. Alzheimer disease is the most common form of dementia. Prevalence 44.4

The international association for the study of pain has defined pain as unpleasant and emotional experience associated with actual or potential tissue damage or described in terms of such damage20. Spinal anesthesia was first produced by Corning in 1885 and first used deliberately by Bier in 1898. Glucose containing solution for spinal anesthesia was introduced by Barker in 1907. Since then hyperbaric solutions are in use for spinal anesthesia. Spinal anesthesia is preferred over general anesthesia