Proteolysis

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  • Aneurysm Essay

    1246 Words  | 5 Pages

    Introduction Despite considerable advances in surgical treatment, the ruptured human abdominal aortic aneurysm (AAA) is still associated with a mortality rate of 65–85% [1, 2] . A diameter is currently the only reliable determinant of the imminent rupture of an AAA and patients exceeding 5.5 cm generally undergo surgical or endovascular intervention [2, 3] . However, the outcome of rupture is poor with less than half of the patients being delivered to the hospital alive [1, 4] . It is well known

  • Proteolysis in Cheese Ripening

    1287 Words  | 5 Pages

    Proteolysis in Cheese Ripening: Proteolysis is one of the most complex biochemical events in cheese ripening that contributes to the typical taste, texture, and aroma of every cheese variety. This fundamental process in cheese ripening is caused by agents from several sources such as indigenous milk enzymes, lasting coagulant, and enzymes from secondary flora. As a result of its importance, proteolysis has been a key subject of active analysis in the past decade as new evaluation techniques are

  • Advantages And Disadvantages Of Surfactant

    2369 Words  | 10 Pages

    Conventional surfactant: Traditionally various chemical process are carried out to synthesis most of the commercial surfactant. Petrochemicals are being used as raw materials for production of surfactant, due to their huge availability, cost, and performance. For example some petrochemical are as follows paraffin, benzene, olefin fatty alcohol, fatty acid, and ethanol-amine, ethylene oxide, propyl-oxide etc. Limitation of Conventional surfactant: 1. Toxic by-product formation: a very complex reaction

  • The Putrefaction Of Carbohydrates

    505 Words  | 3 Pages

    substances as: proteoses, peptones, polypeptides, and amino acids. These are all simple proteins or base amino acids that are easily decomposed . Later in the decay of the body, structures like reticulin, muscle protein, and collagen start to experience proteolysis too. These proteins take longer to decompose because of their complexity. The continuing breakdown of proteins can lead to the production of the gases carbon dioxide, hydrogen sulphide (which is toxic), ammonia, and methane. When the amino acids

  • Alzheimer 's Disease : Genetic Analysis

    1129 Words  | 5 Pages

    proteins (Davis et.al., 1998) that form the catalytic core in the protease γ-secretase (Francis et.al., 2002), which is responsible for the proteolysis of APP (Navivaeva & Turner, 2013). When there is a mutation at the loci for PSEN1 and PSEN2, located on chromosome 14 and 1 respectively, the activity of γ-secretase is altered resulting in changes in the proteolysis of APP and increased formation of Aβ (Qain et.al., 1998). Due to the increase of Aβ, amyloid plaques aggregate quickly causing early-onset

  • How Does Protease Inhibitors Work?

    1227 Words  | 5 Pages

    Enzyme Protease. A disease is the destruction in the function of a human which leads to specific symptoms which in turn affects specific sites and are not results of physical injury. Protease cleaves longer proteins into shorter core proteins via proteolysis this is the process whereby hydrolysis of the peptide bonds occur that links subsequent amino acids to a polypeptide chain (Kohei Oda 2012). It is therefore crucial for the effectiveness of an infectious virus. Protease Inhibitors bind to the active

  • The Pathophysiology Of Huntington's Disease

    1091 Words  | 5 Pages

    Researches about Huntington’s disease (HD) revealed that it is caused by an expanded CAG trinucleotide repeat in HTT, the gene responsible for expressing the protein huntingtin. It was also revealed that the reduced expression of this protein leads to the neurodegenerative effects of the disease. However, the pathophysiology of the disease is still unknown. This paper investigated the pathophysiology of Huntington’s disease. This paper is based upon the toxic peptide theory of the disease pathogenesis

  • Fibrinogen Case Study

    768 Words  | 4 Pages

    fully organized thrombus is formed, its life span is determined by the resistance of the fibrin clot to proteolysis by plasmin. The generation of plasmin from plasminogen by tissue plasminogen activator is enhanced by the presence of fibrin, particularly after partial degradation by plasmin. The structure of the fibrin clot has been reported to significantly modulate both the rate of proteolysis of fibrin by plasmin as well as the rate of plasmin formation.8 Two previous murine in vivo studies point

  • The Expression Of Matriptase Centered On Lung Cancer Cells

    1357 Words  | 6 Pages

    NCI-H1944. Both HAI-1 and HAI-2 can act as inhibitors to both matriptase and prostasin while HAI-1 is the predominant inhibitor. This network should be very essential to the oncogenesis and metastasis of lung cancer cells. Introduction Pericellular proteolysis plays important roles in many

  • How Does Diabetes Mellitus Affect The Individual 's Morbidity And Mortality

    3894 Words  | 16 Pages

    Metabolism is a sequence of biochemical reactions that take place in every single cell and organ to maintain the organism growth, reproduction, damage repair, and adaptation to the surrounding environment. These reactions involve catabolism and anabolism using the major sources of energy: proteins, lipids, and carbohydrates. Furthermore, any disruption in the regulation of the metabolic processes affects the individual’s morbidity and mortality [1]. Accordingly, in this chapter, we are going to discuss

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