Introduction
Breast cancer is one of the leading causes of high mortality and morbidity in women population worldwide. Up to date, no effective breast cancer treatment has been developed and this has motivated academic scientists for the quest for alternative drugs and the discovery of drug targets. Increasing evidence suggests that carotenoids, which are micronutrients in fruit and vegetables, reduce breast cancer risk [1]. Previous findings suggest a protective role of α-carotene, β-carotene, lutein/zeaxanthin and lycopene in breast cancer risk [2, 3]. Lycopene, a known major carotenoid detected in human plasma, is known to hold the most robust anticancer and chemopreventive properties as demonstrated in clinical trials and animal models of various cancers including mammary cancer, prostate cancer [4] and brain cancer. In vitro and in vivo studies have reported that lycopene prevents the growth of different cancer cells of different organs and inhibits chemically induced carcinogenesis in animal models. Although the excellent antioxidant property of lycopene is most likely the basis for its preventive role toward cancer, the direct anticancer activities of lycopene through multiple mechanisms are disclosed, including regulation of growth factor signaling, cell cycle arrest and/or apoptosis induction, and changes in antioxidant and phase II detoxifying enzymes. The anti-inflammatory activity of lycopene is also considered as an important determinant that suppresses the
“Cancer” is the name for a group of diseases that start in the body at the cellular level. Even though there are many different kinds of cancer, they all begin with abnormal cell growth with the potential to invade or spread to other parts of the body. These abnormal cells lump together to form a mass of tissue or “malignant tumor”. Malignant means that it can spread to other parts of the body or Metastasize . If the breast is the original location of the cancer growth or malignant tumor, the tumor is called breast cancer. (American Cancer Society, 2014, as cited in cbcf.org)
The Lawler family has a history with a specific type of cancer, Breast cancer. When Deb was in high school, she watched her mother fight through breast cancer and Deb’s grandmother died from breast cancer before she was born. Her uncle Bob was just diagnosed with breast cancer before his 50th birthday, and her cousin Katherine was diagnosed with the cancer when she was 33. Now that Deb is 33 years old, she has been wanting to know her chances of being diagnosed. When Deb had first brought up the idea about getting tested, her family was split on advice for her. Deb’s father encouraged her and her siblings to be tested, but her brother John really did not know how to feel about the testing, her sister was undecided about how she felt, but thought that her results could have benefits for her children in the future. Her mother was silent when the topic came up in conversation, and Deb’s cousin Lynn, refused to even discuss the subject. Deb’s Aunt Sue, was vocal about her opinion and was very
Breast cancer is the most common malignant disease occurring in women in Saudi society. After study and research, it found that two-thirds of the injuries in the Saudi society are diagnosed in advanced stages. The reasons for that are the lack of education for necessary of Self-examination and clinical examination annual, leading to the spread of the disease further. In addition to genetic changes, environmental pollution, bad lifestyle , Obesity ,Lack of exercise are also factors that helped in the spread of the disease. The delayed age of marriage and lack of breastfeeding are the risk factors for breast cancer(1,10,14).Early detection and diagnosis of breast cancer is important for successful treatment selection , and increase mortality rate of breast cancer.
We have all seen the pink ribbons. They have become a national, if not international symbol for breast cancer support and awareness. Breast cancer knows neither racial boundaries nor age restrictions. Females of all ages and ethnicities can develop breast cancer and it is the leading most common cancer among women. Calling attention to this often fatal disease is important by supporting its victims, families and friends of victims, as well as raising funds for breast cancer research. Though males are not immune from developing a breast cancer, for the purposes of this paper, this paper will be limited to information relating breast cancer in females.
The Susan G. Komen Foundation of Greater Atlanta’s goal is to reduce mortality of African American breast cancer by 25% in the next 5 years (Susan G. Komen Atlanta, 2017). In order to reach this goal, Komen has created many local outreach programs to educate the community about breast health and breast cancer screening (Susan G. Komen Greater Atlanta, 2017). Educational programs like these can have significant impacts on breast cancer mortality rates (Asuquo and Olajide, 2015). However, they may need to focus on certain racial, ethnic, or socioeconomic groups (Herndon, et al., 2013). Worship in Pink is one of Komen’s educational outreach programs that provides breast health and screening information to participating religious organizations (Susan G. Komen, 2017).
Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Breast cancer is the second most commonly diagnosed cancer in women. (Only skin cancer is more common.) About one in eight women in the United States will develop invasive breast cancer in her lifetime. Researchers estimate that more than 230,000 new cases of invasive breast cancer will be diagnosed in U.S. women in 2015. Cancers occur when a buildup of mutations in critical genes—those that control cell growth and division or repair damaged DNA—allow cells to grow and divide uncontrollably to form a tumor. Breast cancer can be caused by inherited genetic factors. These genetic
Breast cancer is cancerous growth of cells in the breast which can be often felt as lump. It becomes dangerous when the cancerous cells becomes malignant and starts invading other tissues of the body. However, this can be prevented by early detection. The incidence of breast cancer is mostly with females although there are few reports of men suffering from the disease. In most cases, the cells with the ducts of milk glands are often associated and few can arise from other cells of the breast and can be termed as sarcomas as well as lymphomas that are different from breast cancer which is an adenocarcinoma (Al-Hajj, Wicha, Benito-Hernandez, Morrison, & Clarke, 2003). Common type of breast cancer includes ductal carcinoma in situ which is considered non-invasive and not life threatening. The invasive ductal carcinoma is associated with the milk duct and can invade nearby tissues of the breast as well as other body parts through the blood stream. Another form of invasive lobular carcinoma starts from the milk glands and can metastasize. Other less common types includes inflammatory breast cancer, Paget disease, phyllodes tumour and angiosarcoma.
Breast cancer (BRCA) is associated with the highest mortality rate of any type of cancer besides that of the lung (American Cancer Society, 2013). BRCA occurs most commonly in women over the age of 40, with an estimated global incidence of 1.6 million cases in 2010. An estimated 39,000 women died from BRCA alone in 2013 (American Cancer Society, 2013). BRCA is responsible for the largest portion of spending on cancer-related care in the United States; an estimated $16.5 billion of cancer-related spending went towards BRCA in 2010 (Mariotto, Robin Yabroff, Shao, Feuer, & Brown, 2011). Although the prevalence, mortality, and costs associated with BRCA are quite high, recent advances in screening and treatment have increased long term
Asma mentioned a metaphor used by her doctor to describe her sexual condition after treatment who said ‘your ovaries are expired like an old lady’. At this point of the interview Asma cried because she felt different and experienced symptoms not associated with her age group.
We have been taught and are reminded frequently by public service announcements and by the medical community that when a woman discovers a lump on her breast she should go to the doctor immediately. Some women who have inflammatory breast cancer may remain undiagnosed for long periods, even while seeing their doctor to learn the cause of her symptoms.
To hear the word cancer come out of a providers mouth can be one of the scariest times of anyone life. So many questions pop into ones head, what do I have or how did I get it, and what do I do know. Breast and cervical cancer are two of the most common cancers diagnosed in women worldwide (Siegel, Miller, & Jemal, 2015). Breast cancer starts to develop when cells in the breast start to grow out of control and form tumors (American Cancer Society , 2015). The population that breast cancer effects is women, even though men can develop breast cancer too it is not nearly as common as women (American Cancer Society , 2015). In fact breast cancer is so common in women that 1 in 8 women in the United states will have developed breast cancer at some point in their lives (American Cancer Society , 2015). Women who are between the ages of 20-59 years old are often the population who die from breast cancer, 1 in 36 women in this age group will have died from breast cancer (Siegel, et al., 2015). Statistics show that white women have the highest incidence rates of breast cancer out of any of the other races and ethnicities (Siegel, et al., 2015). However, African American women have higher death rates from breast cancer than any other race (American Cancer Society , 2015). This difference in races can contribute to many fact that African American women usually do not have the health insurance or the right health education to inform them about the risks of breast cancer,
This paper will inform you of Breast Cancer. It is the most common form of cancer in women today but thanks to medical advances it is no longer the number one killer of women.
These methods include: a breast exam, mammogram, breast ultrasound, biopsy, and MRI. On the website, mayoclinic.org, there was a brief explanation about each of these methods. For breast exams the doctor usually checks both breast and the lymph nodes in the armpits or other abnormalities. An x-ray is used for mammograms in order to screen cancer. Now for the breast ultrasound, they use sound waves to make images and can help distinguish between a solid mass or fluid filled cyst. A magnet and radio waves are used to create images of one’s breast, along with an injection of dye, for an MRI. A biopsy actually can help influence treatment options that one receives. It is a laboratory analysis that helps determine if the cell is very cancerous (mayoclinic.org). Treatments for breast cancer also vary person to person and depend on the stage that the person is in. They can have breast cancer surgery, radiation therapy, chemotherapy, hormone therapy and targeted drugs. Surgery involves removing the cancer or it can be as much as removing both breasts. Radiation therapy uses high beams of energy, like x-rays, in order to kill the cancer cells and chemotherapy uses drugs in order to kill the cancer cells. Hormone therapy is often used to treat breast cancers that are sensitive to hormones and the targeted drugs are used to attack specific abnormalities
increase without sway. These cells will form a tumor that can often be seen on
Cancer, which is the name given to collection of related diseases, is a general term used to refer