Osteoarthritis is an ailment of complex etiology that results in loss of normal function due to the failure of joint articular cartilage. Therefore, it can be defined as a sickness of the cartilage where the kind of tissue with compressive properties and viscoelasticity reported by its extracellular matrix, comprised mostly of proteoglycans and type II collagen (Boissonnault, 2011 p90). As per pathophysiology of osteoarthritis manifested by biochemical, morphological, and molecular changes in both cells and matrix which lead to becoming weaker that also leads to sclerosis, ulceration, fibrillation, damage of joint articular cartilage, eburnation of subchondral osteophyte bone and subchondral cysts. Under typical situations, this matrix is …show more content…
These are obtainable by prescription or over-the-counter like NSAIDs, including naproxen sodium (Aleve and others), and ibuprofen (Advil, Motrin IB, others) when taken at the recommended doses, can get rid of osteoarthritis pain. Heavy-duty NSAIDs, which is available by prescription, may reduce inflammation along with relieving pain. Some antidepressants, such as duloxetine, will help relieve pain. Opioids can be administered to relieve severe pain, but it can be addictive. There are are some powerful anti-inflammatory medicines like corticosteroids that are administered orally or by injection at a doctor’s office directly to the joint. Found naturally in the joint fluid is Hyaluronic acid that serves as a shock absorber and lubricant. The acid can be commercially manufactured and seems to alleviate pain quickly in people diagnosed with OA. Acetaminophen is the common drug of choice, but topical capsaicin and glucosamine/chondroitin also considered. If these drugs are not effective, NSAIDs and cyclooxygenase (COX)-2 inhibitors are tried (Ciccone, 2016 p219). Whereas there is confirmation suggesting that NSAIDs are better than acetaminophen in alleviating pain in patients with OA. The range of controlling the outcome cannot assert because the median trial length was merely six weeks. Because of this, further observations are required when creating the choice between taking NSAIDs or acetaminophen. However, in patients with moderate-to-severe levels of pain, NSAIDs seem to be the better choice than acetaminophen. (Kalunian,
Osteoarthritis (OA) is the most common joint disorder. It occurs when cartilage begins to break down or be worn away and the bone rubs together. As a result bony spurs and inflammation of the joint(s) occurs. Surrounding ligaments and muscles may also weaken or stiffen. Major risk factors are: genetics, excess weight, joint injuries, jobs that involve more than an hour of joint stressing activities like kneeling, and sports that involve direct impact on the joints, twisting, or throwing. Bleeding disorders, disorders that blood supply near joints, and other types of arthritis can cause osteoarthritis. Symptoms typically begin while one is middle aged and almost everyone shows some symptoms of OA by age 70. This is important to note because OA is seemingly inevitable for everybody. OA is not curable and typically gets worse with time, but the symptoms can be managed. Strength in weight bearing joints, the hip, the knee, and the ankle, is particularly important for prevention. Also important are not overusing joints and maintaining a normal body weight.
Osteoarthritis, or degenerative joint disease, is a form of arthritis characterized by the breakdown of cartilage within joints. Cartilage serves to provide cushion at the ends of bones, and when the cushion is not sufficient, as in osteoarthritis, the bones rub together. As a result, osteoarthritis sufferers are constantly plagued by stiff, swollen, and inflamed joints (http://www.arthritis.org/answers/diseasecenter/oa.asp). It is a relatively common condition, with an estimated 20 million American sufferers, most of whom are elderly (http://webmd.lycos.com/content/article/1668.50297). Traditional treatments include Tylenol, aspirin, or other non-steroidal anti-inflammatory drugs
Non-steroidal anti-inflammatory drugs (NSAIDs) are the foundation of medical treatment for osteoarthritis (OA). It is the most common medication taken by an individual experiencing pain due to this degenerative joint disease. Not to mention, NSAIDS are prescribed for pain management in older adults since they are more efficacious than acetaminophen with the absence of central nervous system side effects of opioids
Osteoarthritis, the most common type of arthritis, is most prevalent in older patients. Osteoarthritis is a degenerative bone disease due to the gradual loss of cartilage. A primary type of osteoarthritis is hip arthritis where it is caused by joint injury, increasing age, and being overweight (“Hip Osteoarthritis,” n.d.). However, osteoarthritis can also be caused by immature joints, inherited defects in cartilage, and extra stress on a patient’s joints (Hip Osteoarthritis,” n.d.). As a result, hip arthritis becomes a huge detriment in patient’s social, emotional, physical lifestyles. In order to treat hip arthritis, doctors choose from a variety of non-drug treatments, medications, and surgeries. Uniquely, I was inspired to research about the treatments of hip arthritis because my very own brother was pronounced with hip arthritis a few years back. Therefore, his determination to battle this disease encouraged me to investigate about the treatment of hip arthritis.
Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage on the ends of your bones wears down over time. Most people don't know they have it because the aches, tenderness, stiffness dont feel like arthritis until x-rays prove it. Just like regular arthritis, it affects the skeletal system. This is because it causes the bones to wear and then become stiff.Primary osteoarthritis, osteoarthritis not resulting from injury or disease, is mostly a result of natural aging of the joint. With aging, the water content of the cartilage increases, and the protein makeup of cartilage degenerates. Eventually, cartilage begins to degenerate by flaking or forming tiny crevasses.Secondary
Osteoarthritis, also known as degenerative joint disease, is an endemic condition that affects 20 million people in the United States alone. Osteoarthritis is the most common type of arthritis and is defined as a gradual process of destruction and degeneration or wearing away of the joint cartilage which typically occurs in the older individual age 50 and over (http://emedicine.medscape.com/article/330487-overview#a0101). . Although this diease is well known for its association with the natural aging process, it is also prevalent in athletes. Specifically, osteoarthritis of the knee has been said to be the most commonly affected area as a majpr weight bearing joint and is a growing epidemic in relation to sports injuries in the young adult. http://www.webmd.com/osteoarthritis/guide/ostearthritis-of-the-knee-degenerative-arthritis-of-the-knee. According to, (Vincent), among upper and lower reported extremity sites, the most common region for osteoarthritis to manifest is p’in the medial compartment of the knee. The risk of knee osteoarthritis from knee joint injury is high; approximately 50% of individuals with an ACL or meniscus tear develop knee osteoarthritis [10-15]. A long-term prospective study indicated a relative risk for knee osteoarthritis of approximately 5 for any previous injury of the knee [13]. As cited in, _____, Thelin and colleagues determined that injury of the knee joint was associated with all knee OA in a
Osteoarthritis (OA) is the most common form of arthritis. The prevalent population suffering from OA is the elderly, but it may afflict a person of any age, especially upon injury of the joint. This ailment will usually affect loan bearing joints such as the knee or hips, but it can affect any joint. OA is the breakdown of the protective cartilage within the joint, and the patient will suffer from pain, swelling and/or stiffness of the joint, and a decreased range of motion at the joint. These symptoms can have a debilitating effect on a patient by making menial tasks suck as walking, climbing stairs, or even rising out of bed or a chair difficult. Currently, there are various treatment options available for OA but no cure exists; therefore,
Drug treatments such as topical analgesic ointments and medications, such as acetaminophen have been proven to be effective in treating OA pain. Some alternative treatments, such as heat therapy (soaking the affected area in warm water, paraffin and heat compress), have been shown to help relive sensitive joints. Other nondrug therapies include simple, medium- intensity exercise such as swimming and strength training to help increase and maintain mobility in the areas affected. Unfortunately, while these treatments are helpful, they are not always enough for some. In more severe cases, an orthopedic surgeon may inject cortisone or hyaluronic acid into joint spaces such as the knee (Stark). In the most severe, debilitating cases, surgical intervention is necessary to trim destroyed cartilage from the joints, replace joints altogether, and sometimes to fuse bones together (Stark). While not guaranteed, there are some simple steps to take to help lower your risk of developing OA. Avoid excess
Osteoarthritis is a degenerative joint disease characterized by a fragmentation and erosion of the articular cartilage, which becomes soft, frayed and thinned with alteration of the subchondral bone. It also characterized by the hypertrophy of the bone, changes accompanied by pain and stiffness which finally leads to loss of
When the point of two or more bones comes together, it is called a joint. We are able to make a movement because the present of joints which are designed to allow movement and to assimilate shock from the movement such as running or walking. Furthermore, cartilage is an elastic and though tissue that covered the ends of the bones. The capsule act as protection centre which joints is surrounded by it. A type of tissue called synovium produces synovial fluid lined the joint capsule (Magro, C., M., and Crowson, A., N., 2003). The fluid is clear in substances that help the cartilage and bones inside the joint capsule easily lubricated and nourished. The disease process leading to rheumatoid arthritis begins here. The protective sac consists of lubricating liquid known as synovial fluid. Other than to cushioning joints, cartilage is a slippery tissue located at the ends of the bones also get nutrients and oxygen which is supplied by the fluids. Cartilage also is the structural protein in the body, which is composed primarily of collagen. The functions of this cartilage is form a mesh to give protection and flexibility to the joints. In rheumatoid arthritis, continuous inflammation of the synovium is occurred caused by an abnormal immune system response that secrete destructive molecules (Paleolog, 2002). As a result, collagen dramatically destroyed thus make the joint space
medicine for osteoarthritis (OA) of the knee, to assess the methodologic quality of the trials
Osteoarthritis is a condition that affects the bones. This degenerative condition can cause the bones to become brittle and fragile, which puts a person at a greater risk for a fracture. Fortunately, you can ease osteoarthritis symptoms by changing your diet. There are foods that you will need to avoid. Below is a list of foods that you need to avoid if you are suffering from osteoarthritis:
Osteoarthritis (OA) is a chronic degenerative and progressive condition affecting synovial joints, which mainly causes degeneration of hyaline cartilage; Although OA can affect any joint containing hyaline cartilage; Its effects take place most often in the weight bearing joints of lower extremities and the most common large joints involved are knee joints [1].
Osteoarthritis is the most common joint disorder, and more than half of all Americans who are older than 65 have been diagnosed with osteoarthritis. However, recent US data has revealed knee osteoarthritis does not discriminate age, and there is growing evidence that osteoarthritis affects individuals at a young age. The annual cost of osteoarthritis due to treatment and loss of productivity in the US is estimated to be more than 65 billion dollars.1 With no cure currently available for osteoarthritis, current treatments focus on management of symptoms. The primary goals of therapy include improved joint function, pain relief, and increased joint stability. Although the exact cause of osteoarthritis is unknown, many risk factors have been identified including increased age, female gender, obesity, and trauma.2 Within these risk factors, the etiology of osteoarthritis has been divided into anatomy, body mass, and gender.
OA is a musculoskeletal disease that causes chronic joint pain and reduced physical functioning (Laba, brien, Fransen, & jan, 2013). Osteoarthritis (OA) is a non-inflammatory disorder of synovial joints that results in loss of hyaline cartilage and remodeling of surrounding bone. OA is the single most common joint disease, with an estimated prevalence of 60% in men and 70% in women later in life after the age of 65 years, affecting an estimated 40 million people in the United States (Goodman & Fuller, 2009). Women are more commonly affected after the age of 55, almost everyone has some symptoms by the age of 70 (Tan, Zahara, Colburn & Hawkins, 2013, p.78). Osteoarthritis can be described radiological, clinical, or subjective.