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Age-Related Macular Degeneration (AMD)

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Age-related macular degeneration (AMD) is a common eye condition and a leading cause of vision loss among people age 50 and older. It causes damage to the macula, a small spot near the center of the retina and the part of the eye needed for sharp, central vision, which lets us see objects that are straight ahead. In some people, AMD advances so slowly that vision loss does not occur for a long time. In others, the disease progresses faster and may lead to a loss of vision in one or both eyes. As AMD progresses, a blurred area near the center of vision is a common symptom. Over time, the blurred area may grow larger or you may develop blank spots in your central vision. Objects also may not appear to be as bright as they used to be. AMD by itself does not lead to complete blindness, with no ability to see. However, the loss of central vision in AMD can interfere with …show more content…

AMD is a neurodegenerative disease that preferentially affects the macular (central) region of the retina, although the reason for this is not clearly understood. The disease is categorized into early, intermediate, or advanced stages based on the severity of symptoms, including the number and size of drusen accompanied by hyper- or hypopigmentary changes and the presence or absence of choroidal neovascularization. The yellowish lipid-rich, protein-containing drusen deposits accumulate between the retinal pigment epithelium (RPE) and Bruch’s membrane and are symptomatic of early disease. Drusen are considered the “hallmark” of AMD. The term “dry AMD” refers broadly to early or

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